产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD1a单克隆抗体(MTB1)
目录 :
MA5-14096
规格 :
500微升
价格 :
美国413.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MTB1
反应物种 :
人类
应用 :
免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 1
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Piersma S, Jordanova E, van Poelgeest M, Kwappenberg K, van der Hulst J, Drijfhout J, et al. High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer. Cancer Res. 2007;67:354-61 pubmed
|
图像
图像 1 :
Formalin-fixed, paraffin-embedded human skin stained with CD1a antibody using peroxidase-conjugate and AEC chromogen. Note staining of Langerhans cells in epidermis.
产品信息
产品类型 :
抗体
产品名称 :
CD1a单克隆抗体(MTB1)
目录# :
MA5-14096
规格 :
500微升
价格 :
美国413.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类
应用 :
免疫组化(石蜡): 1:15
物种 :
人类
克隆 :
MTB1
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin. CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells. CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X. CD1a is expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. CD1a is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1a localizes to the plasma membrane and recycles vesicles of the early endocytic system. At least five CD1 genes (CD1a, b, c, d, and e) are identified. Alternatively spliced transcript variants of CD1a have been observed, but their biological validity have not been determined.
免疫原 :
Full external domain of CD1a
格式 :
液体
应用w/稀释 :
免疫组化(石蜡): 1:15
别名 :
CD1; CD1 antigen; CD1.1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cd1a1; CD1A1 antigen; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a
更多信息或购买 :
公司信息
赛默飞世尔