产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD36单克隆抗体(185-1G2)
目录 :
MA5-14112
规格 :
500微升
价格 :
美国396.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
185-1G2
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 5
Pardee A, Yano H, Weinstein A, Ponce A, Ethridge A, Normolle D, et al. Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma. J Immunother Cancer. 2015;3:32 pubmed 出版商
  • 免疫组化; 人类; 10 ug/ml
Hromatka B, Ngeleza S, Adibi J, Niles R, Tshefu A, Fisher S. Histopathologies, immunolocalization, and a glycan binding screen provide insights into Plasmodium falciparum interactions with the human placenta. Biol Reprod. 2013;88:154 pubmed 出版商
  • 流式细胞仪; 人类
Taront S, Dieudonné A, Blanchard S, Jeannin P, Lassalle P, Delneste Y, et al. Implication of scavenger receptors in the interactions between diesel exhaust particles and immature or mature dendritic cells. Part Fibre Toxicol. 2009;6:9 pubmed 出版商
  • 流式细胞仪; 人类
Klein M, Gittis A, Su H, Makobongo M, Moore J, Singh S, et al. The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure. PLoS Pathog. 2008;4:e1000147 pubmed 出版商
  • 免疫组化; 人类
Martens J, Kzhyshkowska J, Falkowski Hansen M, Schledzewski K, Gratchev A, Mansmann U, et al. Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis. J Pathol. 2006;208:574-89 pubmed
  • 抑制或激活实验; 人类; 5 ug/ml
Short S, Derrien A, Narsimhan R, Lawler J, Ingber D, Zetter B. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol. 2005;168:643-53 pubmed
Kitaura A, Nishinaka T, Hamasaki S, Hatipoglu O, Wake H, Nishibori M, et al. Advanced glycation end-products reduce lipopolysaccharide uptake by macrophages. PLoS ONE. 2021;16:e0245957 pubmed 出版商
Huang L, Chambliss K, Gao X, Yuhanna I, Behling Kelly E, Bergaya S, et al. SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis. Nature. 2019;569:565-569 pubmed 出版商
Hamasaki S, Kobori T, Yamazaki Y, Kitaura A, Niwa A, Nishinaka T, et al. Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis. Sci Rep. 2018;8:5901 pubmed 出版商
DuSablon A, Parks J, Whitehurst K, Estes H, Chase R, Vlahos E, et al. EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice. PLoS ONE. 2017;12:e0189307 pubmed 出版商
Isenberg J, Ridnour L, Dimitry J, Frazier W, Wink D, Roberts D. CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J Biol Chem. 2006;281:26069-80 pubmed
Chen X, Doffek K, Sugg S, Shilyansky J. Phosphatidylserine regulates the maturation of human dendritic cells. J Immunol. 2004;173:2985-94 pubmed
图像
图像 1 :
赛默飞世尔 MA5-14112 图像 1
Frozen human tonsil section stained with CD36 antibody using UltraVision LP and AEC chromogen. Note staining of monocytes, marcrophages and endothelial cells.
产品信息
产品类型 :
抗体
产品名称 :
CD36单克隆抗体(185-1G2)
目录# :
MA5-14112
规格 :
500微升
价格 :
美国396.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: 0.5-1 µg/test, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): Assay-dependent
物种 :
人类, 小鼠
克隆 :
185-1G2
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
CD36 (fatty acid translocase, FAT) is an 88 kDa, ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similar to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. Further, CD36 may function as a cell adhesion molecule and directly mediates cyto-adherence of Plasmodium falciparum parasitized erythrocytes. Mutations in the CD36 gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the CD36 protein have been found.
免疫原 :
Stimulated human leukocytes
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5-1 µg/test, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): Assay-dependent
别名 :
adipocyte membrane protein; BDPLT10; Cd36; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule; CD36 molecule (thrombospondin receptor); CD36 protein; CHDS7; cluster determinant 36; collagen type I receptor thrombospondin receptor; collagen type I receptor, thrombospondin receptor; FAT; FAT/CD36; fatty acid translocase; fatty acid translocase/CD36; fatty acid transport protein; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; I79_011940; Leukocyte differentiation antigen CD36; PAS IV; PAS4; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; Platelet glycoprotein 4; platelet glycoprotein IV; Scarb3; scavenger receptor class B, member 3; SR-B3; Thrombospondin receptor
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国