产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
p73单克隆抗体(ER-15)
目录 :
MA5-14117
规格 :
500微升
价格 :
美国454.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
ER-15
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 24
参考文献
Funato K, Hayashi T, Echizen K, Negishi L, Shimizu N, Koyama Nasu R, et al. SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity. EMBO Rep. 2018;19: pubmed 出版商
Liu J, Zhang C, Wang X, Ly P, Belyi V, Xu Monette Z, et al. E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis. Cell Death Differ. 2014;21:1792-804 pubmed 出版商
Rodhe J, Kavanagh E, Joseph B. TAp73?-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics. Oncotarget. 2013;4:289-97 pubmed
Romano D, Maccario H, Doherty C, Quinn N, Kolch W, Matallanas D. The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics. Mol Cell Biol. 2013;33:1859-68 pubmed 出版商
Accardi R, Scalise M, Gheit T, Hussain I, Yue J, Carreira C, et al. IkappaB kinase beta promotes cell survival by antagonizing p53 functions through DeltaNp73alpha phosphorylation and stabilization. Mol Cell Biol. 2011;31:2210-26 pubmed 出版商
Wilhelm M, Rufini A, Wetzel M, Tsuchihara K, Inoue S, Tomasini R, et al. Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev. 2010;24:549-60 pubmed 出版商
Lapi E, Di Agostino S, Donzelli S, Gal H, Domany E, Rechavi G, et al. PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol Cell. 2008;32:803-14 pubmed 出版商
Heyne K, Schmitt K, Mueller D, Armbruester V, Mestres P, Roemer K. Resistance of mitochondrial p53 to dominant inhibition. Mol Cancer. 2008;7:54 pubmed 出版商
Inoue T, Ogawa M, Mikoshiba K, Aruga J. Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008;28:4712-25 pubmed 出版商
Sudhakar C, Jain N, Swarup G. Sp1-like sequences mediate human caspase-3 promoter activation by p73 and cisplatin. FEBS J. 2008;275:2200-13 pubmed 出版商
Zitterbart K, Zavrelova I, Kadlecova J, Spesna R, Kratochvilova A, Pavelka Z, et al. p73 expression in medulloblastoma: TAp73/DeltaNp73 transcript detection and possible association of p73alpha/DeltaNp73 immunoreactivity with survival. Acta Neuropathol. 2007;114:641-50 pubmed
Lee J, Basak J, Demehri S, Kopan R. Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes. Development. 2007;134:2795-806 pubmed
Toscano F, Parmentier B, Fajoui Z, Estornes Y, Chayvialle J, Saurin J, et al. p53 dependent and independent sensitivity to oxaliplatin of colon cancer cells. Biochem Pharmacol. 2007;74:392-406 pubmed
Limesand K, Schwertfeger K, Anderson S. MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. Mol Cell Biol. 2006;26:8840-56 pubmed
Lapi E, Iovino A, Fontemaggi G, Soliera A, Iacovelli S, Sacchi A, et al. S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation. Oncogene. 2006;25:3628-37 pubmed
Yoshida M, Assimacopoulos S, Jones K, Grove E. Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order. Development. 2006;133:537-45 pubmed
Jiang Y, Lo W, Akhmametyeva E, Chang L. Over-expression of p73beta results in apoptotic death of post-mitotic hNT neurons. J Neurol Sci. 2006;240:1-6 pubmed
Sayan A, Paradisi A, Vojtesek B, Knight R, Melino G, Candi E. New antibodies recognizing p73: comparison with commercial antibodies. Biochem Biophys Res Commun. 2005;330:186-93 pubmed
Meyer G, Cabrera Socorro A, Perez Garcia C, Martinez Millan L, Walker N, Caput D. Developmental roles of p73 in Cajal-Retzius cells and cortical patterning. J Neurosci. 2004;24:9878-87 pubmed
Bergamaschi D, Samuels Y, Jin B, Duraisingham S, Crook T, Lu X. ASPP1 and ASPP2: common activators of p53 family members. Mol Cell Biol. 2004;24:1341-50 pubmed
Frasca F, Vella V, Aloisi A, Mandarino A, Mazzon E, Vigneri R, et al. p73 tumor-suppressor activity is impaired in human thyroid cancer. Cancer Res. 2003;63:5829-37 pubmed
Guan M, Peng H, Yu B, Lu Y. p73 Overexpression and angiogenesis in human colorectal carcinoma. Jpn J Clin Oncol. 2003;33:215-20 pubmed
Vella V, Zhu J, Frasca F, Li C, Vigneri P, Vigneri R, et al. Exclusion of c-Abl from the nucleus restrains the p73 tumor suppression function. J Biol Chem. 2003;278:25151-7 pubmed
Kim E, Park J, Um S. Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo. J Biol Chem. 2002;277:32020-8 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
p73单克隆抗体(ER-15)
目录# :
MA5-14117
规格 :
500微升
价格 :
美国454.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
Human, Non-human primate
应用 :
Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL
物种 :
Human, Non-human primate
克隆 :
ER-15
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
P73 (TP73) participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
免疫原 :
Purified monkey recombinant p73alpha protein (aa380-637)
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL
别名 :
deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; Tp73; transformation related protein 73; Trp73; Tumor protein p73
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国