产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Tyrosinase Monoclonal Antibody (T311)
目录 :
MA5-14177
规格 :
500微升
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
T311
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 27
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 1d
Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2016;35:2862-72 pubmed 出版商
  • 免疫印迹; 人类
Abad S, Wieërs G, Colau D, Wildmann C, Delair E, Dhote R, et al. Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient. Mol Vis. 2014;20:956-69 pubmed
  • 免疫组化; 人类; 1:100
Alaggio R, Cecchetto G, Martignoni G, Bisogno G, Cheng L, Sperli D, et al. Malignant perivascular epithelioid cell tumor in children: description of a case and review of the literature. J Pediatr Surg. 2012;47:e31-40 pubmed 出版商
  • 免疫组化; 人类
Manganoni A, Rossi M, Sala R, Venturini M, Sereni E, Ungari M, et al. Dermoscopic, histological and immunohistochemical evaluation of cancerous features in acquired melanocytic nevi that have been repeatedly exposed to UVA or UVB. Exp Dermatol. 2012;21:86-90 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 4
Tjin E, Konijnenberg D, Krebbers G, Mallo H, Drijfhout J, Franken K, et al. T-cell immune function in tumor, skin, and peripheral blood of advanced stage melanoma patients: implications for immunotherapy. Clin Cancer Res. 2011;17:5736-47 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Zhang H, Fu T, McGettigan S, Kumar S, Liu S, Speicher D, et al. IL-8 and cathepsin B as melanoma serum biomarkers. Int J Mol Sci. 2011;12:1505-18 pubmed 出版商
  • 免疫印迹; 人类
Ho H, Kapadia R, Al Tahan S, Ahmad S, Ganesan A. WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition. J Biol Chem. 2011;286:12509-23 pubmed 出版商
  • 免疫组化; 人类; 1:100
Petersson F, Michal M, Vanecek T, Hora M, Trivunić S, Halbhuber Z, et al. Bilateral renal tumors; conventional clear cell carcinoma and contralateral t(6;11)/t(X;17)-like tumor Histomorphologic, immunohistochemical, ultrastructural and molecular genetic studies including the report of a novel mutation in the VHL gene. Ann Diagn Pathol. 2011;15:362-9 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Selvan S, Carbonell D, Fowler A, Beatty A, Ravindranath M, Dillman R. Establishment of stable cell lines for personalized melanoma cell vaccine. Melanoma Res. 2010;20:280-92 pubmed 出版商
  • 免疫组化; 人类
Chen N, Hu Y, Li W, Eisinger M, Seiberg M, Lin C. The role of keratinocyte growth factor in melanogenesis: a possible mechanism for the initiation of solar lentigines. Exp Dermatol. 2010;19:865-72 pubmed 出版商
  • 免疫组化; 人类; 1:100
Kacerovska D, Michal M, Sosna B, Cempirkova D, Ambrus M, Richtr P, et al. Carcinoid-like pattern in melanoma: report of 4 cases. Am J Dermatopathol. 2009;31:542-50 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Vossmerbaeumer U, Ohnesorge S, Kuehl S, Haapalahti M, Kluter H, Jonas J, et al. Retinal pigment epithelial phenotype induced in human adipose tissue-derived mesenchymal stromal cells. Cytotherapy. 2009;11:177-88 pubmed 出版商
  • 免疫组化; 人类
Hasegawa J, Goto Y, Murata H, Takata M, Saida T, Imokawa G. Downregulated melanogenic paracrine cytokine linkages in hypopigmented palmoplantar skin. Pigment Cell Melanoma Res. 2008;21:687-99 pubmed
  • 免疫细胞化学; 人类; 1:2000
  • 免疫印迹; 人类; 1:2000
Hasegawa T, Treis A, Patenge N, Fiesel F, Springer W, Kahle P. Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways. J Neurochem. 2008;105:1700-15 pubmed 出版商
  • 免疫组化; 人类
Michal M, Kazakov D, Sima R, Vanecek T. Primitive small cell tumor with epithelial, gangliocytic, neuroendocrine, and mesenchymal differentiation: report of 2 cases. Int J Surg Pathol. 2007;15:429-36 pubmed
  • 流式细胞仪; 人类
Yuan J, Kendle R, Ireland J, Heller G, Sadelain M, Young J, et al. Scalable expansion of potent genetically modified human langerhans cells in a closed system for clinical applications. J Immunother. 2007;30:634-43 pubmed
  • 免疫细胞化学; 人类; 1:200
Julien S, Kociok N, Kreppel F, Kopitz J, Kochanek S, Biesemeier A, et al. Tyrosinase biosynthesis and trafficking in adult human retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol. 2007;245:1495-505 pubmed
  • 免疫组化; 人类
Luiten R, Kueter E, Mooi W, Gallee M, Rankin E, Gerritsen W, et al. Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients. J Clin Oncol. 2005;23:8978-91 pubmed
  • 免疫组化; 人类; 1:50
Sensi M, Nicolini G, Zanon M, Colombo C, Molla A, Bersani I, et al. Immunogenicity without immunoselection: a mutant but functional antioxidant enzyme retained in a human metastatic melanoma and targeted by CD8(+) T cells with a memory phenotype. Cancer Res. 2005;65:632-40 pubmed
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类; 1:250
  • 免疫印迹; 人类; 1:200
Popescu C, Paduraru C, Dwek R, Petrescu S. Soluble tyrosinase is an endoplasmic reticulum (ER)-associated degradation substrate retained in the ER by calreticulin and BiP/GRP78 and not calnexin. J Biol Chem. 2005;280:13833-40 pubmed
Lawana V, Um S, Rochet J, Turesky R, Shannahan J, Cannon J. Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity. Toxicol Sci. 2020;173:171-188 pubmed 出版商
Otręba M, Pajor M, Warncke J. Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines. Naunyn Schmiedebergs Arch Pharmacol. 2019;: pubmed 出版商
Scarparo A, Sumida D, Patrão M, Avellar M, Visconti M, Maria de Lauro Castrucci A. Catecholamine effects on human melanoma cells evoked by alpha1-adrenoceptors. Arch Dermatol Res. 2004;296:112-9 pubmed
van Oijen M, Bins A, Elias S, Sein J, Weder P, de Gast G, et al. On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients. Clin Cancer Res. 2004;10:4754-60 pubmed
Glazyrin A, Kan Mitchell J, Mitchell M. Analysis of in vitro immunization: generation of cytotoxic T-lymphocytes against allogeneic melanoma cells with tumor lysate-loaded or tumor RNA-transfected antigen-presenting cells. Cancer Immunol Immunother. 2003;52:171-8 pubmed
Sheffield M, Yee H, Dorvault C, Weilbaecher K, Eltoum I, Siegal G, et al. Comparison of five antibodies as markers in the diagnosis of melanoma in cytologic preparations. Am J Clin Pathol. 2002;118:930-6 pubmed
Boi S, Cristofolini P, Togni R, Girlando S, Camerani M, Donner D, et al. Detection of nodal micrometastases using immunohistochemistry and PCR in melanoma of the arm and trunk. Melanoma Res. 2002;12:147-53 pubmed
图像
图像 1 :
赛默飞世尔 MA5-14177 图像 1
图像 2 :
赛默飞世尔 MA5-14177 图像 2
产品信息
产品类型 :
抗体
产品名称 :
Tyrosinase Monoclonal Antibody (T311)
目录# :
MA5-14177
规格 :
500微升
价格 :
美国446.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:25-1:100
物种 :
人类, 小鼠
克隆 :
T311
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
免疫原 :
Recombinant tyrosinase protein
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:25-1:100
别名 :
albino; albino locus protein; ATN; C; CMM8; LB24-AB; monophenol monooxygenase; Oca1; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; skc35; Tumor rejection antigen AB; TYR; Tyrosinase; tyrosinase (oculocutaneous albinism IA); tyrosinase precursor
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国