产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
基质金属蛋白酶9单克隆抗体(IIA5)
目录 :
MA5-14228
规格 :
500微升
价格 :
美国405.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
IIA5
反应物种 :
人类, 小鼠, 大鼠, 犬
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
AbdElazeem M, El Sayed M. The pattern of CD44 and matrix metalloproteinase 9 expression is a useful predictor of ulcerative colitis-associated dysplasia and neoplasia. Ann Diagn Pathol. 2015;19:369-74 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300
  • 免疫印迹; 人类; 1:200
Dayer C, Stamenkovic I. Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation. J Biol Chem. 2015;290:13763-78 pubmed 出版商
  • 免疫组化; 犬; 1 ug/ml
Allam E, Allen M, Chu T, Ghoneima A, Jack Windsor L. In vivo effects of zoledronic acid on oral mucosal epithelial cells. Oral Dis. 2011;17:291-7 pubmed 出版商
  • 免疫印迹; 小鼠; 1:400
Olsen C, Moreira J, Lukanidin E, Ambartsumian N. Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts. BMC Cancer. 2010;10:444 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Li S, Wu Y, Kang Y, Yin Y, Gao W, Liu Y, et al. Noninvasive limb ischemic preconditioning protects against myocardial I/R injury in rats. J Surg Res. 2010;164:162-8 pubmed 出版商
  • 免疫印迹; 大鼠
Duarte A, Duarte E, Correia A, Pires E, Barros M. Cardosins improve neuronal regeneration after cell disruption: a comparative expression study. Cell Biol Toxicol. 2009;25:99-108 pubmed 出版商
  • 免疫细胞化学; 人类; 1:30
Travaglino E, Benatti C, Malcovati L, Della Porta M, Galli A, Bonetti E, et al. Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes. Eur J Haematol. 2008;80:216-26 pubmed
  • 免疫组化; 小鼠; 1:100
Hassane S, Claij N, Lantinga van Leeuwen I, Van Munsteren J, van Lent N, Hanemaaijer R, et al. Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model. Arterioscler Thromb Vasc Biol. 2007;27:2177-83 pubmed
  • 免疫组化; 大鼠; 1:50
Oggionni T, Morbini P, Inghilleri S, Palladini G, Tozzi R, Vitulo P, et al. Time course of matrix metalloproteases and tissue inhibitors in bleomycin-induced pulmonary fibrosis. Eur J Histochem. 2006;50:317-25 pubmed
  • 免疫印迹; 大鼠; 1:250
Kalyanasundaram A, Elmore J, Manazer J, Golden A, Franklin D, Galt S, et al. Simvastatin suppresses experimental aortic aneurysm expansion. J Vasc Surg. 2006;43:117-24 pubmed
  • 免疫印迹; 大鼠; 1:200
Arbos M, Ferrando J, Quiles M, Vidal J, Lopez Cano M, Gil J, et al. Improved surgical mesh integration into the rat abdominal wall with arginine administration. Biomaterials. 2006;27:758-68 pubmed
Zhou H, Li L, Xie W, Wu L, Lin Y, He X. TAGLN and High-mobility Group AT-Hook 2 (HMGA2) Complex Regulates TGF-β-induced Colorectal Cancer Metastasis. Onco Targets Ther. 2020;13:10489-10498 pubmed 出版商
Jäkel L, Kuiperij H, Gerding L, Custers E, van den Berg E, Jolink W, et al. Disturbed balance in the expression of MMP9 and TIMP3 in cerebral amyloid angiopathy-related intracerebral haemorrhage. Acta Neuropathol Commun. 2020;8:99 pubmed 出版商
Deng Z, Zhou L, Wang Y, Liao S, Huang Y, Shan Y, et al. Astrocyte-derived VEGF increases cerebral microvascular permeability under high salt conditions. Aging (Albany NY). 2020;12:11781-11793 pubmed 出版商
Shahin N, Abdelkader N, Safar M. A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling. Sci Rep. 2018;8:4280 pubmed 出版商
Sahlin L, Stjernholm Vladic Y, Roos N, Masironi B, Ekman Ordeberg G. Impaired leukocyte influx in cervix of postterm women not responding to prostaglandin priming. Reprod Biol Endocrinol. 2008;6:36 pubmed 出版商
Kirkegaard T, Hansen A, Bruun E, Brynskov J. Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease. Gut. 2004;53:701-9 pubmed
Surgucheva I, Sivak J, Fini M, Palazzo R, Surguchov A. Effect of gamma-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells. Arch Biochem Biophys. 2003;410:167-76 pubmed
图像
图像 1 :
赛默飞世尔 MA5-14228 图像 1
产品信息
产品类型 :
抗体
产品名称 :
基质金属蛋白酶9单克隆抗体(IIA5)
目录# :
MA5-14228
规格 :
500微升
价格 :
美国405.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 大鼠
应用 :
Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1-2 µg/mL
物种 :
人类, 大鼠
克隆 :
IIA5
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
MMP9 (matrix metallopeptidase 9, GELB, CLG4B) is a matrix metalloproteinase, a family of zinc and calcium-dependent endopeptidases that degrade extracellular matrix proteins. MMP9 is secreted as a 92kDa zymogen and cleavage of pro-MMP9 results in the active enzyme with a molecular weight of 82kDa. MMP9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodeling, wound healing, tumor growth and metastasis. MMP9 is supplied by bone marrow-derived cells and contributes to skin carcinogenesis. Further, MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. Studies have shown that elevated MMP9 is associated with progression of idiopathic atrial fibrillation and aortic aneurysm.
免疫原 :
人类天然92kDa基质金属蛋白酶-9
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: Assay-dependent, Western Blot: 1-2 µg/mL
别名 :
67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; 92kD gelatinase; 92kD type IV collagenase; 92kDa gelatinase; 92kDa type IV collagenase; 92-kDa type IV collagenase; AW743869; B/MMP9; Clg4b; collagenase type IVB; fj05a08; Gel B; gelatinase B; Gelatinase-B; GELB; macrophage gelatinase; MANDP2; matrix metallo protease; matrix metallopeptidase 9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9; matrix metalloproteinase 9 (gelatinase B 92-kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92kDa matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92-kDa type IV collagenase); Matrix metalloproteinase9; matrix metalloproteinase-9; MMP; Mmp9; MMP-9; mmp9 protein; MMP-9 protein; MMPs; Preproform of 92-kDa type IV collagenase (MMP-9): N-terminal; pro-MMP-9; type IV collagenase; type V collagenase; wu:fb02g06; wu:fb07b05; wu:fi98c09; wu:fj05a08; ZFMMP-9; zgc:64165
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国