产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
RAD51单克隆抗体(51RAD01(3C10))
目录 :
MA5-14419
规格 :
500微升
价格 :
美国405.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
51RAD01(3C10)
反应物种 :
Rhynchospora tenuis, 衣藻, fission yeast, Rhynchospora pubera, 嗜热四膜虫, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:200; 图 2a
Atkins A, Xu M, Li M, Rogers N, Pryzhkova M, Jordan P. SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. elife. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 嗜热四膜虫; 1:50; 图 2a
Tian M, Loidl J. A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation. Nucleic Acids Res. 2018;46:11822-11834 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 4b
Skvarova Kramarzova K, Osborn M, Webber B, Defeo A, McElroy A, Kim C, et al. CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells. Int J Mol Sci. 2017;18: pubmed 出版商
  • 免疫细胞化学; 嗜热四膜虫
Shodhan A, Kataoka K, Mochizuki K, Novatchkova M, Loidl J. A Zip3-like protein plays a role in crossover formation in the SC-less meiosis of the protist Tetrahymena. Mol Biol Cell. 2017;28:825-833 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Ishiguro K, Zhu Y, Lin Z, Penketh P, Shyam K, Zhu R, et al. Cataloging antineoplastic agents according to their effectiveness against platinum-resistant and platinum-sensitive ovarian carcinoma cell lines. J Transl Sci. 2016;2:117-124 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 6
  • 免疫细胞化学; 人类; 1:100; 图 5
  • 免疫印迹; 人类; 1:500; 图 5
Annovazzi L, Caldera V, Mellai M, Riganti C, Battaglia L, Chirio D, et al. The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment. Int J Oncol. 2015;46:2299-308 pubmed 出版商
  • 免疫组化; Rhynchospora tenuis; 1:75; 图 s1
  • 免疫组化; Rhynchospora pubera
Cabral G, Marques A, Schubert V, Pedrosa Harand A, Schlögelhofer P. Chiasmatic and achiasmatic inverted meiosis of plants with holocentric chromosomes. Nat Commun. 2014;5:5070 pubmed 出版商
  • 免疫组化; 人类; 1:100
Nakanoko T, Saeki H, Morita M, Nakashima Y, Ando K, Oki E, et al. Rad51 expression is a useful predictive factor for the efficacy of neoadjuvant chemoradiotherapy in squamous cell carcinoma of the esophagus. Ann Surg Oncol. 2014;21:597-604 pubmed 出版商
  • 免疫组化; 人类; 1:75
Mattila R, Rautava J, Syrjänen S. Human papillomavirus in oral atrophic lichen planus lesions. Oral Oncol. 2012;48:980-984 pubmed 出版商
  • 免疫细胞化学; 人类
Hsu J, Lin T, Tsai R. Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1. J Cell Biol. 2012;197:613-24 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
  • 免疫印迹; 人类; 1:200
Howard Till R, Lukaszewicz A, Loidl J. The recombinases Rad51 and Dmc1 play distinct roles in DNA break repair and recombination partner choice in the meiosis of Tetrahymena. PLoS Genet. 2011;7:e1001359 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Lin Y, Sengupta S, Gurdziel K, Bell G, Jacks T, Flores E. p63 and p73 transcriptionally regulate genes involved in DNA repair. PLoS Genet. 2009;5:e1000680 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Erenpreisa J, Cragg M, Salmina K, Hausmann M, Scherthan H. The role of meiotic cohesin REC8 in chromosome segregation in gamma irradiation-induced endopolyploid tumour cells. Exp Cell Res. 2009;315:2593-603 pubmed 出版商
  • 免疫细胞化学; 衣藻; 1:50
Mochizuki K, Novatchkova M, Loidl J. DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena. J Cell Sci. 2008;121:2148-58 pubmed 出版商
  • 免疫沉淀; 人类
Fischer J, Lancia J, Mathur A, Smith M. Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex. Anticancer Res. 2006;26:899-904 pubmed
  • 免疫细胞化学; fission yeast; 1:50
Lorenz A, Estreicher A, Kohli J, Loidl J. Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe. Chromosoma. 2006;115:330-40 pubmed
  • 免疫印迹; 人类
Dutta A, Chakraborty A, Saha A, Ray S, Chatterjee A. Interaction of radiation- and bleomycin-induced lesions and influence of glutathione level on the interaction. Mutagenesis. 2005;20:329-35 pubmed
  • 免疫印迹; 人类
Chinnaiyan P, Huang S, Vallabhaneni G, Armstrong E, Varambally S, Tomlins S, et al. Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva). Cancer Res. 2005;65:3328-35 pubmed
Bondarieva A, Raveendran K, Telychko V, Rao H, Ravindranathan R, Zorzompokou C, et al. Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse. Nat Commun. 2020;11:3101 pubmed 出版商
El Bezawy R, Tripari M, Percio S, Cicchetti A, Tortoreto M, Stucchi C, et al. SPOP Deregulation Improves the Radiation Response of Prostate Cancer Models by Impairing DNA Damage Repair. Cancers (Basel). 2020;12: pubmed 出版商
Mi Y, Dong H, Sun X, Ren F, Tang Y, Zheng P. The association of Helicobacter pylori CagA EPIYA motifs and vacA genotypes with homologous recombination repair markers during the gastric precancerous cascade. Int J Biol Markers. 2020;35:49-55 pubmed 出版商
Leonardi S, Buttarelli M, De Stefano I, Ferrandina G, Petrillo M, Babini G, et al. The relevance of prelamin A and RAD51 as molecular biomarkers in cervical cancer. Oncotarget. 2017;8:94247-94258 pubmed 出版商
Tanaka N, Patel A, Tang L, Silver N, Lindemann A, Takahashi H, et al. Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation. Clin Cancer Res. 2017;23:6541-6554 pubmed 出版商
Howard Till R, Lukaszewicz A, Novatchkova M, Loidl J. A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena. PLoS Genet. 2013;9:e1003418 pubmed 出版商
Loidl J, Lukaszewicz A, Howard Till R, Koestler T. The Tetrahymena meiotic chromosome bouquet is organized by centromeres and promotes interhomolog recombination. J Cell Sci. 2012;125:5873-80 pubmed 出版商
Loidl J, Scherthan H. Organization and pairing of meiotic chromosomes in the ciliate Tetrahymena thermophila. J Cell Sci. 2004;117:5791-801 pubmed
Wilkinson D, Weller S. Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage respon. J Virol. 2004;78:4783-96 pubmed
Ivanov A, Cragg M, Erenpreisa J, Emzinsh D, Lukman H, Illidge T. Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks. J Cell Sci. 2003;116:4095-106 pubmed
Sarkisian C, Master S, Huber L, Ha S, Chodosh L. Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals. J Biol Chem. 2001;276:37640-8 pubmed
图像
图像 1 :
赛默飞世尔 MA5-14419 图像 1
图像 2 :
赛默飞世尔 MA5-14419 图像 2
图像 3 :
赛默飞世尔 MA5-14419 图像 3
产品信息
产品类型 :
抗体
产品名称 :
RAD51单克隆抗体(51RAD01(3C10))
目录# :
MA5-14419
规格 :
500微升
价格 :
美国405.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
51RAD01(3C10)
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
免疫原 :
重组Rad51蛋白
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL
别名 :
AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国