产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(EP700Y)
目录 :
MA5-14458
规格 :
1毫升
价格 :
美国572.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP700Y
反应物种 :
人类
应用 :
免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 4
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
Song D, Ko G, Lee J, Lee J, Lee G, Kim H, et al. Myoferlin expression in non-small cell lung cancer: Prognostic role and correlation with VEGFR-2 expression. Oncol Lett. 2016;11:998-1006 pubmed
  • 免疫细胞化学; 人类
Lupu Meiri M, Geras Raaka E, Lupu R, Shapira H, Sandbank J, Segal L, et al. Knock-down of plasminogen-activator inhibitor-1 enhances expression of E-cadherin and promotes epithelial differentiation of human pancreatic adenocarcinoma cells. J Cell Physiol. 2012;227:3621-8 pubmed 出版商
Ilina O, Campanello L, Gritsenko P, Vullings M, Wang C, Bult P, et al. Intravital microscopy of collective invasion plasticity in breast cancer. Dis Model Mech. 2018;11: pubmed 出版商
Khalil A, Ilina O, Gritsenko P, Bult P, Span P, Friedl P. Collective invasion in ductal and lobular breast cancer associates with distant metastasis. Clin Exp Metastasis. 2017;34:421-429 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-14458 图像 1
Formalin-fixed, paraffin-embedded human breast carcinoma stained with E-cadherin antibody using peroxidase-conjugate and DAB chromogen. Note membrane staining.
产品信息
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(EP700Y)
目录# :
MA5-14458
规格 :
1毫升
价格 :
美国572.00
克隆性 :
单克隆
宿主 :
兔
反应物种 :
人类
应用 :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:50
物种 :
人类
克隆 :
EP700Y
抗体亚型 :
IgG
储存 :
4° C
描述 :
E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
免疫原 :
A synthetic peptide derived from the fifth cadherin domain of human cadherin
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:50
别名 :
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-Cadherin phospho; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; phospho cadherin 1; phospho E-Cadherin; phospho LCAM; phospho S838; phospho UVO; S840; S840 E-Cadherin; Ser840; Ser840 E-Cadherin; Um; UVO; Uvomorulin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国