产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞角蛋白5单克隆抗体(EP1601Y)
目录 :
MA5-14473
规格 :
1毫升
价格 :
美国950.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP1601Y
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 图 2
Eriksson P, Aine M, Veerla S, Liedberg F, Sjödahl G, Höglund M. Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems. BMC Med Genomics. 2015;8:25 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Zuo W, Zhang T, Wu D, Guan S, Liew A, Yamamoto Y, et al. p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration. Nature. 2015;517:616-20 pubmed 出版商
  • 免疫组化; 人类
Herfs M, Vargas S, Yamamoto Y, Howitt B, Nucci M, Hornick J, et al. A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia. J Pathol. 2013;229:460-8 pubmed 出版商
  • 免疫组化; 人类
Herfs M, Yamamoto Y, Laury A, Wang X, Nucci M, McLaughlin Drubin M, et al. A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proc Natl Acad Sci U S A. 2012;109:10516-21 pubmed 出版商
  • 免疫组化; 人类
Sjödahl G, Lauss M, Lövgren K, Chebil G, Gudjonsson S, Veerla S, et al. A molecular taxonomy for urothelial carcinoma. Clin Cancer Res. 2012;18:3377-86 pubmed 出版商
  • 免疫组化; 人类; 1:40
Kim B, Park E, Kwon I, Cho H, Park H, Kim K, et al. An immunohistochemical study of the origin of the solid strand in syringoma, using carcinoembryonic antigen, epithelial membrane antigen, and cytokeratin 5. Int J Dermatol. 2012;51:817-22 pubmed 出版商
  • 免疫组化; 小鼠
Lee E, Park J, Lee J, Oh S, Baek S, Kim B, et al. Characterization of the expression of cytokeratins 5, 8, and 14 in mouse thymic epithelial cells during thymus regeneration following acute thymic involution. Anat Cell Biol. 2011;44:14-24 pubmed 出版商
Wang Y, Lu Y, Wu Y, Sun Y, Zhou Y, Ma Q, et al. Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions. Stem Cells Int. 2019;2019:7123078 pubmed 出版商
Volckaert T, Yuan T, Yuan J, Boateng E, Hopkins S, Zhang J, et al. Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and β-catenin signaling. Development. 2019;146: pubmed 出版商
Tajpara P, Mildner M, Schmidt R, Vierhapper M, Matiasek J, Popow Kraupp T, et al. A Preclinical Model for Studying Herpes Simplex Virus Infection. J Invest Dermatol. 2019;139:673-682 pubmed 出版商
Volckaert T, Yuan T, Chao C, Bell H, Sitaula A, Szimmtenings L, et al. Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells. Dev Cell. 2017;43:48-59.e5 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-14473 图像 1
Formalin-fixed, paraffin-embedded human mesothelioma stained with Keratin 5 using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining.
产品信息
产品类型 :
抗体
产品名称 :
细胞角蛋白5单克隆抗体(EP1601Y)
目录# :
MA5-14473
规格 :
1毫升
价格 :
美国950.00
克隆性 :
单克隆
宿主 :
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry: 1:50, Western Blot: 1:500
物种 :
人类, 小鼠
克隆 :
EP1601Y
抗体亚型 :
IgG
储存 :
4° C
描述 :
Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
免疫原 :
A synthetic peptide corresponding to residues on the C-term of human CK5
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry: 1:50, Western Blot: 1:500
别名 :
3300001P10Rik; 58 kDa cytokeratin; alpha keratin; AW146334; C DDD; C KRT5A; CK5; CK-5; ckii; ckii protein; cytokeratin 5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin complex 2, basic, gene 5; keratin type II, tail domain; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 5; keratin 5; keratin-5; Krt2-5; KRT5; KRT5A; Sak57; Tfip8; tuftelin interacting protein 8; type II alpha-keratin IIA; type II cytokeratin; type-II keratin Kb5; wu:fb02h09; wu:fj02d02; wu:fk78b12; zfCKII
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国