产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
雌激素受体α单克隆抗体(Sp1转录因子)
目录 :
MA5-14501
规格 :
500微升
价格 :
美国794.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
Sp1转录因子
反应物种 :
人乳头状瘤病毒, 人类, 小鼠, 大鼠, 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, reverse phase protein lysate microarray, 其他
更多信息或购买 :
文章摘录数: 323
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:100; 表 1
Kim M, Chung Y, Kim H, Woo J, Ahn S, Park S. Immune microenvironment in ductal carcinoma in situ: a comparison with invasive carcinoma of the breast. Breast Cancer Res. 2020;22:32 pubmed 出版商
  • 免疫印迹; 人类; 图 7b
Guan J, Zhou W, Hafner M, Blake R, Chalouni C, Chen I, et al. Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility. Cell. 2019;178:949-963.e18 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫印迹; 人类; 1:10; 图 2a
Sinkala E, Sollier Christen E, Renier C, Rosàs Canyelles E, Che J, Heirich K, et al. Profiling protein expression in circulating tumour cells using microfluidic western blotting. Nat Commun. 2017;8:14622 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 7a
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Sánchez Morgan N, Kirsch K, Trackman P, Sonenshein G. UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells. J Cell Biochem. 2017;118:2347-2356 pubmed 出版商
  • 流式细胞仪; 人类; 1:50; 图 ED7c
  • 免疫沉淀; 人类
  • 免疫印迹; 人类; 1:500; 图 2c, 4b, 4e,ED4b
Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα. Nature. 2017;541:541-545 pubmed 出版商
  • 免疫印迹; 人类
Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 st1
Nielsen T, Jensen M, Burugu S, Gao D, Jørgensen C, Balslev E, et al. High-Risk Premenopausal Luminal A Breast Cancer Patients Derive no Benefit from Adjuvant Cyclophosphamide-based Chemotherapy: Results from the DBCG77B Clinical Trial. Clin Cancer Res. 2017;23:946-953 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 2
Petrovic N, Davidovic R, Jovanovic Cupic S, Krajnovic M, Lukic S, Petrovic M, et al. Changes in miR-221/222 Levels in Invasive and In Situ Carcinomas of the Breast: Differences in Association with Estrogen Receptor and TIMP3 Expression Levels. Mol Diagn Ther. 2016;20:603-615 pubmed
  • 免疫印迹; 人类; 图 2
Trapé A, Liu S, Cortés A, Ueno N, Gonzalez Angulo A. Effects of CDK4/6 Inhibition in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Cells with Acquired Resistance to Paclitaxel. J Cancer. 2016;7:947-56 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 s2
Carbognin L, Sperduti I, Brunelli M, Marcolini L, Nortilli R, Pilotto S, et al. Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of Ki67 assay according to histology: prognostic relevance for resected early stage 'pure' and 'mixed' lobular breast cancer. J Exp Clin Cancer Res. 2016;35:50 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s1
Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed 出版商
  • 免疫组化; 人类; 1:100
Matsumoto H, Thike A, Li H, Yeong J, Koo S, Dent R, et al. Increased CD4 and CD8-positive T cell infiltrate signifies good prognosis in a subset of triple-negative breast cancer. Breast Cancer Res Treat. 2016;156:237-47 pubmed 出版商
  • 免疫组化; 人类; 表 3
Alkner S, Bendahl P, Ehinger A, Lövgren K, Rydén L, Fernö M. Prior Adjuvant Tamoxifen Treatment in Breast Cancer Is Linked to Increased AIB1 and HER2 Expression in Metachronous Contralateral Breast Cancer. PLoS ONE. 2016;11:e0150977 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Kim S, Kim E, Lee H, Kim M, Yoon J, Koo J, et al. Asymptomatic Benign Papilloma Without Atypia Diagnosed at Ultrasonography-Guided 14-Gauge Core Needle Biopsy: Which Subgroup can be Managed by Observation?. Ann Surg Oncol. 2016;23:1860-6 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 表 1
El Gendi S, Mostafa M. Runx2 Expression as a Potential Prognostic Marker in Invasive Ductal Breast Carcinoma. Pathol Oncol Res. 2016;22:461-70 pubmed 出版商
  • 免疫细胞化学; 人类; 1:10; 图 s13b
Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al. Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nat Commun. 2015;6:8786 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
O Shaughnessy J, Campone M, Brain E, Neven P, Hayes D, Bondarenko I, et al. Abiraterone acetate, exemestane or the combination in postmenopausal patients with estrogen receptor-positive metastatic breast cancer. Ann Oncol. 2016;27:106-13 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2
Jung Y, Kim H, Koo J. Expression of Lipid Metabolism-Related Proteins in Metastatic Breast Cancer. PLoS ONE. 2015;10:e0137204 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Coelho R, Calaça I, Celestrini D, Correia Carneiro A, Costa M, Zancan P, et al. Hexokinase and phosphofructokinase activity and intracellular distribution correlate with aggressiveness and invasiveness of human breast carcinoma. Oncotarget. 2015;6:29375-87 pubmed 出版商
  • 免疫组化; 人类
Gómez R, Ossa C, Montoya M, Echeverri C, Ángel G, Ascuntar J, et al. Impact of immunohistochemistry-based molecular subtype on chemosensitivity and survival in Hispanic breast cancer patients following neoadjuvant chemotherapy. Ecancermedicalscience. 2015;9:562 pubmed 出版商
  • 免疫组化; 人类; 1:100
KapucuoÄŸlu N, Bozkurt K, BaÅŸpınar Å, Koçer M, EroÄŸlu H, Akdeniz R, et al. The clinicopathological and prognostic significance of CD24, CD44, CD133, ALDH1 expressions in invasive ductal carcinoma of the breast: CD44/CD24 expression in breast cancer. Pathol Res Pract. 2015;211:740-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:60
McBryan J, Fagan A, McCartan D, Bane F, VareÅ¡lija D, Cocchiglia S, et al. Transcriptomic Profiling of Sequential Tumors from Breast Cancer Patients Provides a Global View of Metastatic Expression Changes Following Endocrine Therapy. Clin Cancer Res. 2015;21:5371-9 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Felzen V, Hiebel C, Koziollek Drechsler I, Reißig S, Wolfrum U, Kögel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:25; 图 1c
Kawai M, Nakashima A, Kamada S, Kikkawa U. Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family. J Biomed Sci. 2015;22:48 pubmed 出版商
  • 免疫组化; 人类; 1:500
Mundim F, Pasini F, Brentani M, Soares F, Nonogaki S, Waitzberg A. MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases. Mol Clin Oncol. 2015;3:506-514 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50; 表 2
Cheung S, Boey Y, Koh V, Thike A, Lim J, Iqbal J, et al. Role of epithelial-mesenchymal transition markers in triple-negative breast cancer. Breast Cancer Res Treat. 2015;152:489-98 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Koh V, Lim J, Thike A, Cheok P, Thu M, Tan V, et al. Characteristics and behaviour of screen-detected ductal carcinoma in situ of the breast: comparison with symptomatic patients. Breast Cancer Res Treat. 2015;152:293-304 pubmed 出版商
  • 免疫组化; 人类; 1:500
de Deus Moura R, Carvalho F, Bacchi C. Breast cancer in very young women: Clinicopathological study of 149 patients ≤25 years old. Breast. 2015;24:461-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Nwafor C, Keshinro S. Pattern of hormone receptors and human epidermal growth factor receptor 2 status in sub-Saharan breast cancer cases: Private practice experience. Niger J Clin Pract. 2015;18:553-8 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Frithiof H, Welinder C, Larsson A, Rydén L, Aaltonen K. A novel method for downstream characterization of breast cancer circulating tumor cells following CellSearch isolation. J Transl Med. 2015;13:126 pubmed 出版商
  • 免疫组化; 人类; 1:80
Geels Y, van der Putten L, van Tilborg A, Lurkin I, Zwarthoff E, Pijnenborg J, et al. Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium. Gynecol Oncol. 2015;137:245-51 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Eom K, Jang M, Park S, Kang E, Kim S, Kim J, et al. The Expression of Carbonic Anhydrase (CA) IX/XII and Lymph Node Metastasis in Early Breast Cancer. Cancer Res Treat. 2016;48:125-32 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Rusz O, Vörös A, Varga Z, Kelemen G, Uhercsák G, Nikolényi A, et al. One-Year Neoadjuvant Endocrine Therapy in Breast Cancer. Pathol Oncol Res. 2015;21:977-84 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 表 4
Kim S, Lee Y, Koo J. Differential expression of lipid metabolism-related proteins in different breast cancer subtypes. PLoS ONE. 2015;10:e0119473 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 3
Heskamp S, Boerman O, Molkenboer Kuenen J, Wauters C, Strobbe L, Mandigers C, et al. Upregulation of IGF-1R expression during neoadjuvant therapy predicts poor outcome in breast cancer patients. PLoS ONE. 2015;10:e0117745 pubmed 出版商
  • 免疫组化; 人类; 1:50
Oon M, Thike A, Tan S, Tan P. Cancer stem cell and epithelial-mesenchymal transition markers predict worse outcome in metaplastic carcinoma of the breast. Breast Cancer Res Treat. 2015;150:31-41 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:80
Simons M, Nagtegaal I, Overbeek L, Flucke U, Massuger L, Bulten J. A patient with a noninvasive mucinous ovarian borderline tumor presenting with late pleural metastases. Int J Gynecol Pathol. 2015;34:143-50 pubmed 出版商
  • 免疫组化; 人类; 1:400
Argon A, Åžener A, ZekioÄŸlu O, Kapkaç M, Özdemir N. The effect of freezing on the immunoprofile of breast carcinoma cells. Balkan Med J. 2014;31:335-9 pubmed 出版商
  • 免疫组化; 人类; 1:100
Park S, Kim H, Koo J. Differential expression of cancer-associated fibroblast-related proteins according to molecular subtype and stromal histology in breast cancer. Breast Cancer Res Treat. 2015;149:727-41 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hole S, Pedersen A, Hansen S, Lundqvist J, Yde C, Lykkesfeldt A. New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane. Int J Oncol. 2015;46:1481-90 pubmed 出版商
  • 免疫组化; 人类; 1:200
Liu J, Yu Y, Sun J, He S, Wang X, Yin J, et al. Clinicopathologic characteristics and prognosis of primary squamous cell carcinoma of the breast. Breast Cancer Res Treat. 2015;149:133-40 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Baccelli I, Stenzinger A, Vogel V, Pfitzner B, Klein C, Wallwiener M, et al. Co-expression of MET and CD47 is a novel prognosticator for survival of luminal breast cancer patients. Oncotarget. 2014;5:8147-60 pubmed
  • 免疫组化; 人类; 1:500
Carvalho F, Bacchi L, Pincerato K, van de Rijn M, Bacchi C. Geographic differences in the distribution of molecular subtypes of breast cancer in Brazil. BMC Womens Health. 2014;14:102 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Mingels M, Masadah R, Geels Y, Otte Holler I, de Kievit I, van der Laak J, et al. High prevalence of atypical hyperplasia in the endometrium of patients with epithelial ovarian cancer. Am J Clin Pathol. 2014;142:213-21 pubmed 出版商
  • 免疫印迹; 人类
Wright P, Jones S, Ardern N, Ward R, Clarke R, Sotgia F, et al. 17?-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells. Oncotarget. 2014;5:3055-65 pubmed
  • 免疫组化; 人类; 1:400
Chan A, Tong J, Sung M, Lai P, To K. Epstein-Barr virus-associated lymphoepithelioma-like cholangiocarcinoma: a rare variant of intrahepatic cholangiocarcinoma with favourable outcome. Histopathology. 2014;65:674-83 pubmed 出版商
  • 免疫组化; 人类
Ahn H, Kim M, Kim M, Cho S, Kim Y, Lee G, et al. Loss of ERβ expression in papillary thyroid carcinoma is associated with recurrence in young female. Clin Endocrinol (Oxf). 2015;82:300-6 pubmed 出版商
  • 免疫组化; 人类; 1:80
van der Post R, Bult P, Vogelaar I, Ligtenberg M, Hoogerbrugge N, van Krieken J. HNF4A immunohistochemistry facilitates distinction between primary and metastatic breast and gastric carcinoma. Virchows Arch. 2014;464:673-9 pubmed 出版商
  • 免疫组化; 人类; 1:25
Zhang H, Cohen A, Krishnakumar S, Wapnir I, Veeriah S, Deng G, et al. Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition. Breast Cancer Res. 2014;16:R36 pubmed 出版商
  • 免疫组化; 人类; 1:200
Kim E, Kim J, Lee Y, Chong G, Park J, Hong D. Comparison of estrogen receptor-?, progesterone receptor and calponin expression in gonadotrophin-releasing hormone agonist-sensitive and -resistant uterine fibroids. Obstet Gynecol Sci. 2014;57:144-50 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Park B, Pan B, Toms D, Huynh E, Byun J, Lee Y, et al. Ovarian-cell-like cells from skin stem cells restored estradiol production and estrus cycling in ovariectomized mice. Stem Cells Dev. 2014;23:1647-58 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500
Liu Y, Nenutil R, Appleyard M, Murray K, Boylan M, Thompson A, et al. Lack of correlation of stem cell markers in breast cancer stem cells. Br J Cancer. 2014;110:2063-71 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Neumeister V, Parisi F, England A, Siddiqui S, Anagnostou V, Zarrella E, et al. A tissue quality index: an intrinsic control for measurement of effects of preanalytical variables on FFPE tissue. Lab Invest. 2014;94:467-74 pubmed 出版商
  • 免疫组化; 人类; 1:150
Irshad S, Gillett C, Pinder S, A hern R, Dowsett M, Ellis I, et al. Assessment of microtubule-associated protein (MAP)-Tau expression as a predictive and prognostic marker in TACT; a trial assessing substitution of sequential docetaxel for FEC as adjuvant chemotherapy for early breast cancer. Breast Cancer Res Treat. 2014;144:331-41 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Kirkegaard T, Hansen S, Larsen S, Reiter B, Sørensen B, Lykkesfeldt A. T47D breast cancer cells switch from ER/HER to HER/c-Src signaling upon acquiring resistance to the antiestrogen fulvestrant. Cancer Lett. 2014;344:90-100 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Kővári B, Rusz O, Schally A, Kahan Z, Cserni G. Differential immunostaining of various types of breast carcinomas for growth hormone-releasing hormone receptor - Apocrine epithelium and carcinomas emerging as uniformly positive. APMIS. 2014;122:824-31 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Park H, Jang M, Kim E, Kim H, Lee H, Kim Y, et al. High EGFR gene copy number predicts poor outcome in triple-negative breast cancer. Mod Pathol. 2014;27:1212-22 pubmed 出版商
  • 免疫组化; 人类; 1:100
Caffrey E, Ingoldsby H, Wall D, Webber M, Dinneen K, Murillo L, et al. Prognostic significance of deregulated dicer expression in breast cancer. PLoS ONE. 2013;8:e83724 pubmed 出版商
  • 免疫组化; 人类
Boecker W, Stenman G, Loening T, Andersson M, Sinn H, Barth P, et al. Differentiation and histogenesis of syringomatous tumour of the nipple and low-grade adenosquamous carcinoma: evidence for a common origin. Histopathology. 2014;65:9-23 pubmed 出版商
  • 免疫组化; 人类; 1:50
Kommoss S, Gilks C, Penzel R, Herpel E, Mackenzie R, Huntsman D, et al. A current perspective on the pathological assessment of FOXL2 in adult-type granulosa cell tumours of the ovary. Histopathology. 2014;64:380-8 pubmed 出版商
  • 免疫组化; 人类
Hrstka R, Brychtova V, Fabian P, Vojtesek B, Svoboda M. AGR2 predicts tamoxifen resistance in postmenopausal breast cancer patients. Dis Markers. 2013;35:207-12 pubmed 出版商
  • 免疫组化; 人类
Epitropou G, Kavvadias V, Iliou D, Stathopoulos E, Balas C. A real-time spectral mapper as an emerging diagnostic technology in biomedical sciences. Conf Proc IEEE Eng Med Biol Soc. 2013;2013:1422-5 pubmed 出版商
  • 免疫组化; 人类
Madeira M, Mattar A, Logullo A, Soares F, Gebrim L. Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness-a randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer. BMC Cancer. 2013;13:425 pubmed 出版商
  • 免疫组化; 人类
Kusafuka K, Onitsuka T, Muramatsu K, Miki T, Murai C, Suda T, et al. Salivary duct carcinoma with rhabdoid features: report of 2 cases with immunohistochemical and ultrastructural analyses. Head Neck. 2014;36:E28-35 pubmed 出版商
  • 免疫组化; 人类; 1:50
Brunelli M, Manfrin E, Bria E, Massari F, Tortora G, Brunello E, et al. HER2/neu gene determination in women screened for breast carcinoma: how screening programs reduce the skyrocketing cost of targeted therapy. Anticancer Res. 2013;33:3705-10 pubmed
  • 免疫组化-石蜡切片; 人类; 1:60
Dewaele B, Przybyl J, Quattrone A, Finalet Ferreiro J, Vanspauwen V, Geerdens E, et al. Identification of a novel, recurrent MBTD1-CXorf67 fusion in low-grade endometrial stromal sarcoma. Int J Cancer. 2014;134:1112-22 pubmed 出版商
  • 免疫组化; 人类; 1:100
Argenta P, Um I, Kay C, Harrison D, Faratian D, Sueblinvong T, et al. Predicting response to the anti-estrogen fulvestrant in recurrent ovarian cancer. Gynecol Oncol. 2013;131:368-73 pubmed 出版商
  • 免疫组化; 人类; 1:50
Brunello E, Bogina G, Bria E, Vergine M, Zamboni G, Pedron S, et al. The identification of a small but significant subset of patients still targetable with anti-HER2 inhibitors when affected by triple negative breast carcinoma. J Cancer Res Clin Oncol. 2013;139:1563-8 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Bjerre C, Vinther L, Belling K, Würtz S, Yadav R, Lademann U, et al. TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression. Tumour Biol. 2013;34:3839-51 pubmed 出版商
  • 免疫组化; 人类; 1:200
Do S, Kim K, Kim D, Chae S, Park Y, Park C, et al. Associations between the Expression of Mucins (MUC1, MUC2, MUC5AC, and MUC6) and Clinicopathologic Parameters of Human Breast Ductal Carcinomas. J Breast Cancer. 2013;16:152-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 2
Zhang J, Wang Y, Yin Q, Zhang W, Zhang T, Niu Y. An associated classification of triple negative breast cancer: the risk of relapse and the response to chemotherapy. Int J Clin Exp Pathol. 2013;6:1380-91 pubmed
  • 免疫组化; 人类
Hussein O, Mosbah M, Farouk O, Farag K, El Saed A, Arafa M, et al. Hormone receptors and age distribution in breast cancer patients at a university hospital in northern egypt. Breast Cancer (Auckl). 2013;7:51-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Kourelis K, Tsue T, Girod D, Tawfik O, Sykes K, Shnayder Y. Negative prognostic factors for head and neck cancer in the young. J BUON. 2013;18:459-64 pubmed
  • 免疫组化; 人类; 1:50
Shin S, Lal A, De Vries S, Suzuki J, Roy R, Hwang E, et al. Florid lobular carcinoma in situ: molecular profiling and comparison to classic lobular carcinoma in situ and pleomorphic lobular carcinoma in situ. Hum Pathol. 2013;44:1998-2009 pubmed 出版商
  • 免疫组化; 人类
Fawzy M, Aly N, Shalaby S, El Sawy W, Abdul Maksoud R. Cyclooxygenase-2 169C>G and 8473T>C gene polymorphisms and prostaglandin E2 level in breast cancer: a case-control study. Gene. 2013;527:601-5 pubmed 出版商
  • 免疫组化; 人类; 1:200
Lai H, Tseng L, Chang T, Kuo Y, Hsieh C, Chen S, et al. The prognostic significance of metaplastic carcinoma of the breast (MCB)--a case controlled comparison study with infiltrating ductal carcinoma. Breast. 2013;22:968-73 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 表 1
Aguiar F, Mendes H, Cirqueira C, Bacchi C, Carvalho F. Basal cytokeratin as a potential marker of low risk of invasion in ductal carcinoma in situ. Clinics (Sao Paulo). 2013;68:638-43 pubmed 出版商
  • 免疫组化; 人类
Hao J, Yang C, Liu F, Yang Y, Li S, Li W, et al. Accessory breast cancer occurring concurrently with bilateral primary invasive breast carcinomas: a report of two cases and literature review. Cancer Biol Med. 2012;9:197-201 pubmed 出版商
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图像
图像 1 :
赛默飞世尔 MA5-14501 图像 1
图像 2 :
赛默飞世尔 MA5-14501 图像 2
Formalin-fixed, paraffin-embedded human breast carcinoma stained with Estrogen Receptor using peroxidase-conjugate and AEC. Note nuclear staining of tumor cells
产品信息
产品类型 :
抗体
产品名称 :
雌激素受体α单克隆抗体(Sp1转录因子)
目录# :
MA5-14501
规格 :
500微升
价格 :
美国794.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
反应物种 :
人类
应用 :
Flow Cytometry: 1:200, Immunocytochemistry: 1:25-1:250, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:1,000
物种 :
人类
克隆 :
Sp1转录因子
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa)). Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function. They also play a role in other tissues such as bone. Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
免疫原 :
Synthetic peptide derived from C-terminal of human estrogen receptor
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:200, Immunocytochemistry: 1:25-1:250, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:1,000
别名 :
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国