This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
VDR单克隆抗体(9A7gamma.E10.E4), 生物素
目录 :
MA5-14614
规格 :
500微升
价格 :
美国496
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
9A7gamma.E10.E4
产品信息
产品类型 :
抗体
产品名称 :
VDR单克隆抗体(9A7gamma.E10.E4), 生物素
目录# :
MA5-14614
规格 :
500微升
价格 :
美国496
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
两栖动物, 鸡, 鱼类, 仓鼠, 人类, 小鼠, 猪, 大鼠
应用 :
Gel Shift: 1mg/mL, Western Blot: 1-2 µg/mL
物种 :
两栖动物, 鸡, 鱼类, 仓鼠, 人类, 小鼠, 猪, 大鼠
克隆 :
9A7gamma.E10.E4
抗体亚型 :
IgG2b
储存 :
4° C
描述 :
Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors. Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system. Repression of T-cell proliferation and interleukin-2 (IL-2) gene expression, for example, occurs when VDR binds within the IL-2 enhancer. Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)2D3 has been shown to interfere with assembly of nuclear factor of activated T-cells (NFATp)/Fos/Jun/DNA complex and subsequent IL-2 gene transcription. The corresponding gene for the vitamin D receptor is NR1I1.
免疫原 :
维生素D受体蛋白来自鸡肠
格式 :
液体
应用w/稀释 :
Gel Shift: 1mg/mL, Western Blot: 1-2 µg/mL
别名 :
1,25-dihydroxyvitamin D3 receptor; HGNC:12679; I79_025795; NR1I1; Nuclear receptor subfamily 1 group I member 1; PPP1R163; protein phosphatase 1, regulatory subunit 163; VDR; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D (1,25-dihydroxyvitamin D3) receptor; vitamin D nuclear receptor variant 1; vitamin D receptor; Vitamin D3 receptor
公司信息
赛默飞世尔
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