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抗体

BAD单克隆抗体(E.564.7)

MA5-14800

100微升

美国395.00

单克隆

domestic rabbit

未共轭

E.564.7

人类, 小鼠, 大鼠, 牛

免疫印迹, 免疫细胞化学

BAD单克隆抗体(E.564.7)

MA5-14800

100微升

美国395.00

单克隆

亲和色谱

兔

Bovine, Human, Mouse, Non-human primate, Rat

Immunocytochemistry: 1:50, Western Blot: 1:1,000

Bovine, Human, Mouse, Non-human primate, Rat

E.564.7

IgG

-20°C

The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Synthetic peptide corresponding to residues surrounding Pro102 of human Bad

液体

Immunocytochemistry: 1:50, Western Blot: 1:1,000

AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400