产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化血小板源性生长因子受体/血小板衍生的生长因子受体b(Tyr849, Tyr857)单克隆抗体(T.564.8)
目录 :
MA5-14905
规格 :
100微升
价格 :
美国446
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
T.564.8
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
文章摘录数: 6
参考文献
Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, et al. ZNF768 links oncogenic RAS to cellular senescence. Nat Commun. 2021;12:4841 pubmed 出版商
Tai Y, Gallo N, Wang M, Yu J, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. 2019;102:358-372.e9 pubmed 出版商
Sandlesh P, Juang T, Safina A, Higgins M, Gurova K. Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene. PLoS ONE. 2018;13:e0199785 pubmed 出版商
Fuentes N, Mlih M, Barhoumi R, Fan Y, Hardin P, Steele T, et al. Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition. Cancer Res. 2018;78:3899-3912 pubmed 出版商
Tian H, Tackmann N, Jin A, Zheng J, Zhang Y. Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice. J Biol Chem. 2017;292:21614-21622 pubmed 出版商
Liu S, Jiang Y, Ballou L, Zong W, Lin R. Activation of Gαq in Cardiomyocytes Increases Vps34 Activity and Stimulates Autophagy. J Cardiovasc Pharmacol. 2017;69:198-211 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-14905 图像 1
产品信息
产品类型 :
抗体
产品名称 :
磷酸化血小板源性生长因子受体/血小板衍生的生长因子受体b(Tyr849, Tyr857)单克隆抗体(T.564.8)
目录# :
MA5-14905
规格 :
100微升
价格 :
美国446
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunoprecipitation: 1:50, Western Blot: 1:1000
物种 :
人类, 小鼠, 大鼠
克隆 :
T.564.8
抗体亚型 :
IgG
储存 :
-20°C
描述 :
PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
免疫原 :
Synthetic phosphopeptide corresponding to residues surrounding pTyr857 of human PDGF receptor ß
格式 :
液体
应用w/稀释 :
Immunoprecipitation: 1:50, Western Blot: 1:1000
别名 :
AI115593; AI528809; Alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); Alpha-type platelet-derived growth factor receptor; APDGFR; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140 antigen-like family member B; CD140a; CD140a antigen; CD140b; GAS9; IBGC4; IMF1; JTK12; KOGS; MGC74795; PDGF alpha chain; PDGF beta chain; PDGF Receptor alpha; PDGFACE; Pdgfr; PDGFR1; PDGFR-1; PDGFR2; PDGFR-2; Pdgfra; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; Pdgfrb; PDGF-R-beta; PDGFR-beta; PENTT; PGFRB; platelet derived growth factor receptor alpha; platelet derived growth factor receptor beta; platelet derived growth factor receptor, alpha polypeptide; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 1; platelet-derived growth factor receptor 2; Platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; platelet-derived growth factor receptor, alpha polypeptide; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国