产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Torc1单克隆抗体(T.292.2)
目录 :
MA5-14913
规格 :
100微升
价格 :
美国351.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
T.292.2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
Torc1单克隆抗体(T.292.2)
目录# :
MA5-14913
规格 :
100微升
价格 :
美国351.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Western Blot: 1:1,000
物种 :
人类, 小鼠, 大鼠
克隆 :
T.292.2
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock. [UniProt]
免疫原 :
Synthetic peptide corresponding to residues surrounding Val463 of human TORC1 (CRTC1) protein
格式 :
液体
应用w/稀释 :
Western Blot: 1:1,000
别名 :
AI413414; CH211-255D18.10; CH211-255D18.9; CREB regulated transcription coactivator 1; CREB regulated transcription coactivator 1b; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1b; CRTC1; crtc1b; FLJ14027; KIAA0616; MECT 1; Mect1; mKIAA0616; mucoepidermoid carcinoma translocated 1; mucoepidermoid carcinoma translocated protein 1; Mucoepidermoid carcinoma translocated protein 1 homolog; R74955; si:ch211-255d18.8; TORC1; TORC-1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; transducer of regulated cAMP response element-binding protein 1; WAMTP1; zfTorc1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国