产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Catenin alpha-1 Monoclonal Antibody (J.783.6)
目录 :
MA5-14986
规格 :
100微升
价格 :
美国371
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
J.783.6
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
Catenin alpha-1 Monoclonal Antibody (J.783.6)
目录# :
MA5-14986
规格 :
100微升
定价 :
美国371
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
反应物种 :
Human, Mouse, Non-human primate
应用 :
Immunoprecipitation: 1:50, Western Blot: 1:1,000
物种 :
Human, Mouse, Non-human primate
克隆 :
J.783.6
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
免疫原 :
Synthetic peptide corresponding to the amino-terminal sequence of human a-E-catenin
格式 :
液体
应用w/稀释 :
Immunoprecipitation: 1:50, Western Blot: 1:1,000
别名 :
[a]E-catenin; 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; alpha-E-catenin; cadherin associated protein; Cadherin-associated protein; CAP102; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha; catenin (cadherin-associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha 1; catenin alpha 1 S homeolog; catenin alpha-1; catenin, alpha 1; Catna1; cell-adhesion protein alphaE catenin; ctnna; ctnna1; ctnna1.S; MDPT2; Renal carcinoma antigen NY-REN-13; XELAEV_18020018mg
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国