NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

N-黄蜂单克隆抗体(C.427.3)

MA5-15011

100微升

美国391

单克隆

domestic rabbit

未共轭

C.427.3

中国人仓鼠, 人类, 小鼠, 大鼠, 牛

免疫印迹, 免疫沉淀

N-黄蜂单克隆抗体(C.427.3)

MA5-15011

100微升

美国391

单克隆

亲和色谱

兔

Bovine, Hamster, Human, Mouse, Non-human primate, Rat

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Bovine, Hamster, Human, Mouse, Non-human primate, Rat

C.427.3

IgG

-20°C

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

Synthetic peptide corresponding the sequence of human N-WASP

液体

Immunoprecipitation: 1:50, Western Blot: 1:1,000

2900021I12Rik; 3110031I02Rik; DKFZp779G0847; MGC48327; n wasp; neural Wiskott-Aldrich syndrome protein; NWASP; N-WASP; TRS4; WASL; WASP like actin nucleation promoting factor; WASPB; Wiskott-Aldrich syndrome like; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)