产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TGF乙1单克隆抗体(F.888.7)
目录 :
MA5-15065
规格 :
100微升
价格 :
美国419
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
F.888.7
反应物种 :
人类, 小鼠, 大鼠, pigs
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
McLane J, Rivet C, Gilbert R, Ligon L. A biomaterial model of tumor stromal microenvironment promotes mesenchymal morphology but not epithelial to mesenchymal transition in epithelial cells. Acta Biomater. 2014;10:4811-4821 pubmed 出版商
Saeed K, Jo M, Park J, Alam S, Khan I, Ahmad R, et al. 17β-Estradiol Abrogates Oxidative Stress and Neuroinflammation after Cortical Stab Wound Injury. Antioxidants (Basel). 2021;10: pubmed 出版商
Shrestha R, Bridle K, Cao L, Crawford D, Jayachandran A. Dual Targeting of Sorafenib-Resistant HCC-Derived Cancer Stem Cells. Curr Oncol. 2021;28:2150-2172 pubmed 出版商
Shrestha R, Prithviraj P, Bridle K, Crawford D, Jayachandran A. Combined Inhibition of TGF-β1-Induced EMT and PD-L1 Silencing Re-Sensitizes Hepatocellular Carcinoma to Sorafenib Treatment. J Clin Med. 2021;10: pubmed 出版商
Hritzo B, Aghdam S, Legesse B, Kaur A, Cao M, Boerma M, et al. Late Health Effects of Partial Body Irradiation Injury in a Minipig Model Are Associated with Changes in Systemic and Cardiac IGF-1 Signaling. Int J Mol Sci. 2021;22: pubmed 出版商
Chang L, Wang Q, Ju J, Li Y, Cai Q, Hao L, et al. Magnoflorine Ameliorates Inflammation and Fibrosis in Rats With Diabetic Nephropathy by Mediating the Stability of Lysine-Specific Demethylase 3A. Front Physiol. 2020;11:580406 pubmed 出版商
Li H, Kan B, Song L, Liu Y, Jian X. Role of the Hippo signaling pathway in safflower yellow pigment treatment of paraquat-induced pulmonary fibrosis. J Int Med Res. 2020;48:300060520905425 pubmed 出版商
McLane J, Ligon L. Palladin mediates stiffness-induced fibroblast activation in the tumor microenvironment. Biophys J. 2015;109:249-64 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-15065 图像 1
图像 2 :
赛默飞世尔 MA5-15065 图像 2
图像 3 :
赛默飞世尔 MA5-15065 图像 3
产品信息
产品类型 :
抗体
产品名称 :
TGF乙1单克隆抗体(F.888.7)
目录# :
MA5-15065
规格 :
100微升
定价 :
美国419
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
反应物种 :
人类, 小鼠, 猪, 大鼠
应用 :
Western Blot: 1:1,000
物种 :
人类, 小鼠, 猪, 大鼠
克隆 :
F.888.7
抗体亚型 :
IgG
储存 :
-20°C
描述 :
TGF beta-1 (TGFB1, Transforming Growth Factor Beta 1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its pro-domain. Activation of TGF beta-1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF beta-1, an amino-terminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP. TGF beta-1 helps regulates proliferation, differentiation, adhesion, migration in many cell types. Many cells have TGF beta receptors, and the protein positively and negatively regulates many other growth factors. TGF beta-1 is cleaved into a latency-associated peptide and a mature TGF beta-1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGF beta-1 homodimer. The mature peptide may also form heterodimers with other TGF beta family members. The gene for TGF beta-1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease and cystic fibrosis.
免疫原 :
Synthetic peptide corresponding to a region in the carboxy terminus of TGF-ß1 protein
格式 :
液体
应用w/稀释 :
Western Blot: 1:1,000
别名 :
CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF ß; TGF ß 1; TGF ß1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFß1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor ß1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国