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抗体

磷酸化BAD(Ser112)单克隆抗体(G.445.9)

MA5-15085

100微升

美国375.00

单克隆

domestic rabbit

未共轭

磷酸化

G.445.9

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片

磷酸化BAD(Ser112)单克隆抗体(G.445.9)

MA5-15085

100微升

美国375.00

单克隆

亲和色谱

兔

Human, Mouse, Non-human primate, Rat

Flow Cytometry: 1:800, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000-1:2,000

Human, Mouse, Non-human primate, Rat

G.445.9

IgG

-20°C

The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Synthetic phosphopeptide corresponding to residues surrounding pSer112 of mouse Bad

液体

Flow Cytometry: 1:800, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000-1:2,000

AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400