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抗体

磷酸化NFkB p105(Ser933)单克隆抗体(C.478.3)

MA5-15128

100微升

美国375.00

单克隆

domestic rabbit

未共轭

磷酸化

C.478.3

人类, 小鼠, 大鼠

免疫印迹, 免疫沉淀

磷酸化NFkB p105(Ser933)单克隆抗体(C.478.3)

MA5-15128

100微升

美国375.00

单克隆

亲和色谱

兔

Human, Mouse, Non-human primate, Rat

Immunoprecipitation: 1:100, Western Blot: 1:1,000

Human, Mouse, Non-human primate, Rat

C.478.3

IgG

-20°C

NF-kB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation. NFKB1 (p50), a 50KDa functional sub-unit of NF-kB, is a member of Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains. NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-kB factor. NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-bidning. Pathological role of NF-kB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.

Synthetic phosphopeptide corresponding to amino acids around pSer933 of NFkB p105

液体

Immunoprecipitation: 1:100, Western Blot: 1:1,000

CVID12; DNA-binding factor KBF1; EBP-1; KBF1; NF kappaB1; NF KB; NFkappaB; NF-kappaB; NF-kappa-B; NF-kappaB p50; NF-kappaB1; NF-kappa-B1 p84/NF-kappa-B1 p98; NF-kappabeta; NF-kB; Nfkb1; NF-KB1; NFKB-p105; NFKB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 1; nuclear factor kappa-B 1; nuclear factor kappa-B DNA binding subunit; nuclear factor kappaB p50; nuclear factor NF-kappa-B p105 subunit; nuclear factor NF-kappa-B p105 subunit-like protein; nuclear factor NF-kappa-B p50 subunit; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; nuclear factor of kappa light polypeptide enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105); nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105; nuclear factor-kappaB p50; p105; p50; p50 subunit of NF kappaB; p50 subunit of NF-kappaB; p50/p105; RHD of nuclear factor NF-kappa-B p105 subunit