产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
LIMK2单克隆抗体(T.756.1)
目录 :
MA5-15136
规格 :
100微升
价格 :
美国375.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
T.756.1
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 流式细胞仪
更多信息或购买 :
图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
LIMK2单克隆抗体(T.756.1)
目录# :
MA5-15136
规格 :
100微升
价格 :
美国375.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
Human, Mouse, Non-human primate
应用 :
Flow Cytometry: 1:25, Western Blot: 1:1,000
物种 :
Human, Mouse, Non-human primate
克隆 :
T.756.1
抗体亚型 :
IgG
储存 :
-20°C
描述 :
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.
免疫原 :
Synthetic peptide corresponding to carboxy-terminal residues of human LIMK2
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:25, Western Blot: 1:1,000
别名 :
EC 2.7.11.1; kinase LIMK2; LIM domain kinase 2; LIM kinase 2; LIM motif-containing protein kinase 2; LIMK; LIMK 2; LIMK1; LIMK-1; Limk2; LIMK-2; Limk2b; LINhp-2; Link2; OTTHUMP00000199483
更多信息或购买 :
公司信息
赛默飞世尔