产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Bcl-xL Monoclonal Antibody (C.85.1)
目录 :
MA5-15142
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
C.85.1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 3
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
图像
图像 1 :
图像 2 :
产品信息
产品类型 :
抗体
产品名称 :
Bcl-xL Monoclonal Antibody (C.85.1)
目录# :
MA5-15142
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
Human, Mouse, Non-human primate, Rat
应用 :
Flow Cytometry: 1:800, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1:1200, Immunohistochemistry (Paraffin): 1:1200, Immunoprecipitation: 1:100, Western Blot: 1:1,000
物种 :
Human, Mouse, Non-human primate, Rat
克隆 :
C.85.1
抗体亚型 :
IgG
储存 :
-20°C
描述 :
BCL-XL is a part of the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL-XL is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
免疫原 :
Synthetic peptide corresponding to residues surrounding Asp61 of human Bcl-xL
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:800, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1:1200, Immunohistochemistry (Paraffin): 1:1200, Immunoprecipitation: 1:100, Western Blot: 1:1,000
别名 :
anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
更多信息或购买 :
公司信息
赛默飞世尔