产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD10单克隆抗体(2A1H5E1)
目录 :
MA5-15231
规格 :
100微克
价格 :
美国413.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2A1H5E1
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 1
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Islek A, Yilmaz A, Elpek G, Erin N. Childhood chronic gastritis and duodenitis: Role of altered sensory neuromediators. World J Gastroenterol. 2016;22:8349-8360 pubmed
|
图像
图像 1 :
Immunofluorescence analysis of MCF-7 cells using SOX9 antibody (red). Blue: DRAQ5 fluorescent DNA dye.
图像 2 :
Immunohistochemical analysis of paraffin-embedded human breast ductal myoepithelium (A) and lymph tissue (B), showing cytoplasmic (A) and membrane (B) localization using CD10 antibody with DAB staining (A) and AEC staining (B).
图像 3 :
Western blot analysis using SOX9 antibody against K562 (1), HCT116 (2), SW620 (3), LOVO (4), NTERA-2 (5), HEK293 (6) and HepG2 (7) cell lysate.
产品信息
产品类型 :
抗体
产品名称 :
CD10单克隆抗体(2A1H5E1)
目录# :
MA5-15231
规格 :
100微克
价格 :
美国413.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: 1:10,000, Immunohistochemistry: 1:200-1:1,000
物种 :
人类
克隆 :
2A1H5E1
抗体亚型 :
IgG2b
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
CD10 (Common Acute Lymphocytic Leukemia Antigen, CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. CD10 is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. Further, CD10 is a 100 kDa type II transmembrane glycoprotein that exists in a single copy of greater than 45 kb. The 5' untranslated region of the CD10 gene is alternatively spliced, resulting in four separate mRNA transcripts and the coding region is not affected by alternative splicing. Diseases associated with CD10 dysfunction include spinocerebellar ataxia 43 and Charcot-Marie tooth Disease.
免疫原 :
纯化重组片段对应于人Coding sequence蛋白质编码序列-10在大肠杆菌中表达
格式 :
液体
应用w/稀释 :
ELISA: 1:10,000, Immunohistochemistry: 1:200-1:1,000
别名 :
6030454K05Rik; Atriopeptidase; C85356; CALLA; CD10; CMT2T; common acute lymphoblastic leukemia antigen; common acute lymphocytic leukemia antigen; Enkephalinase; EPN; membrane metallo endopeptidase; membrane metalloendopeptidase; membrane metallo-endopeptidase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; MME; NEP; neprilysin; neprilysin-390; neprilysin-411; neutral endopeptidase 24.11; SFE; Skin fibroblast elastase
更多信息或购买 :
公司信息
赛默飞世尔