产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Melan-A Monoclonal Antibody (M2-7C10)
目录 :
MA5-15237
规格 :
500微升
价格 :
美国406.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
M2-7C10
反应物种 :
African green monkey, 人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 27
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:40; 图 4g
Patwardhan A, Bardin S, Miserey Lenkei S, Larue L, Goud B, Raposo G, et al. Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Nat Commun. 2017;8:15835 pubmed 出版商
  • 免疫组化; 小鼠
Pedersen M, Küsters Vandevelde H, Viros A, Groenen P, Sanchez Laorden B, Gilhuis J, et al. Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes. Cancer Discov. 2013;3:458-469 pubmed 出版商
  • 免疫印迹; 人类
Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Ishii Y, et al. Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells. Cancer Res. 2013;73:62-73 pubmed 出版商
  • 免疫组化; 人类; 1:100
Ozluk Y, Kilicaslan I, Kazancioglu R, Demirkesen C, Derin D, Mandel N. Intraglomerular crescentic metastases of malignant melanoma. Hum Pathol. 2011;42:2025-8 pubmed 出版商
  • 免疫组化; 人类; 1:400
Eskue K, Prieto V, Malpica A. Cellular blue nevus of the uterus: a case report and review of the literature. Int J Gynecol Pathol. 2010;29:583-6 pubmed 出版商
  • 免疫组化; 人类; 1:200
Choi W, Miyamura Y, Wolber R, Smuda C, Reinhold W, Liu H, et al. Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB. J Invest Dermatol. 2010;130:1685-96 pubmed 出版商
  • 免疫印迹; 人类
Hoashi T, Sato S, Yamaguchi Y, Passeron T, Tamaki K, Hearing V. Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein. FASEB J. 2010;24:1616-29 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Ryan P, Nguyen V, Gholoum S, Carpineta L, Abish S, Ahmed N, et al. Polypoid PEComa in the rectum of a 15-year-old girl: case report and review of PEComa in the gastrointestinal tract. Am J Surg Pathol. 2009;33:475-82 pubmed 出版商
  • 流式细胞仪; 人类
  • 免疫印迹; 人类; 1:500
Dissanayake S, Olkhanud P, O Connell M, Carter A, French A, Camilli T, et al. Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res. 2008;68:10205-14 pubmed 出版商
  • 免疫印迹; African green monkey
Hosoi A, Takeda Y, Sakuta K, Ueha S, Kurachi M, Kimura K, et al. Dendritic cell vaccine with mRNA targeted to the proteasome by polyubiquitination. Biochem Biophys Res Commun. 2008;371:242-6 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Yamaguchi Y, Coelho S, Zmudzka B, Takahashi K, Beer J, Hearing V, et al. Cyclobutane pyrimidine dimer formation and p53 production in human skin after repeated UV irradiation. Exp Dermatol. 2008;17:916-24 pubmed 出版商
  • 免疫组化; 人类; 1:100
Scheithauer B, Rodriguez F, Spinner R, Dyck P, Salem A, Edelman F, et al. Glomus tumor and glomangioma of the nerve. Report of two cases. J Neurosurg. 2008;108:348-56 pubmed 出版商
  • 免疫组化; 人类; 1:1000
Bandyopadhyay D, Curry J, Lin Q, Richards H, Chen D, Hornsby P, et al. Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi. Aging Cell. 2007;6:577-91 pubmed
  • 流式细胞仪; 人类
Zhang J, Eguchi J, Kruse C, Gomez G, Fakhrai H, Schroter S, et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin Cancer Res. 2007;13:566-575 pubmed 出版商
  • 免疫组化; 人类
Wankowicz Kalinska A, Mailliard R, Olson K, Graham F, Edington H, Kirkwood J, et al. Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation. Melanoma Res. 2006;16:165-74 pubmed
  • 免疫组化; 人类
Arrigo T, Pirazzoli P, de Sanctis L, Leone O, Wasniewska M, Messina M, et al. McCune-Albright syndrome in a boy may present with a monolateral macroorchidism as an early and isolated clinical manifestation. Horm Res. 2006;65:114-9 pubmed
  • 免疫组化; 人类
Luiten R, Kueter E, Mooi W, Gallee M, Rankin E, Gerritsen W, et al. Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients. J Clin Oncol. 2005;23:8978-91 pubmed
  • 免疫组化; 人类; 1:400
Tadokoro T, Yamaguchi Y, Batzer J, Coelho S, Zmudzka B, Miller S, et al. Mechanisms of skin tanning in different racial/ethnic groups in response to ultraviolet radiation. J Invest Dermatol. 2005;124:1326-32 pubmed
  • 免疫沉淀; 人类
Hoashi T, Watabe H, Muller J, Yamaguchi Y, Vieira W, Hearing V. MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes. J Biol Chem. 2005;280:14006-16 pubmed
Wang T, Xie S, Luo R, Shi L, Bai P, Wang X, et al. Two novel TSC2 mutations in renal epithelioid angiomyolipoma sensitive to everolimus. Cancer Biol Ther. 2020;21:4-11 pubmed 出版商
Cho J, Patel B, Bonala S, Manne S, Zhou Y, Vadrevu S, et al. Notch transactivates Rheb to maintain the multipotency of TSC-null cells. Nat Commun. 2017;8:1848 pubmed 出版商
Tiwari R, Geliebter J, Lucchese A, Mittelman A, Kanduc D. Computational peptide dissection of Melan-a/MART-1 oncoprotein antigenicity. Peptides. 2004;25:1865-71 pubmed
Mittelman A, Tiwari R, Lucchese G, Willers J, Dummer R, Kanduc D. Identification of monoclonal anti-HMW-MAA antibody linear peptide epitope by proteomic database mining. J Invest Dermatol. 2004;123:670-5 pubmed
van Oijen M, Bins A, Elias S, Sein J, Weder P, de Gast G, et al. On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients. Clin Cancer Res. 2004;10:4754-60 pubmed
Biddle D, Evans H, Kemp B, El Naggar A, Harvell J, White W, et al. Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma. Am J Surg Pathol. 2003;27:673-81 pubmed
Georgieva J, Milling A, Orfanos C, Geilen C. Magnetic bead RT-PCR: establishment of a new method for detecting circulating melanoma cells. Melanoma Res. 2002;12:309-17 pubmed
Mortarini R, Borri A, Tragni G, Bersani I, Vegetti C, Bajetta E, et al. Peripheral burst of tumor-specific cytotoxic T lymphocytes and infiltration of metastatic lesions by memory CD8+ T cells in melanoma patients receiving interleukin 12. Cancer Res. 2000;60:3559-68 pubmed
图像
图像 1 :
赛默飞世尔 MA5-15237 图像 1
Formalin-fixed, paraffin-embedded human melanoma stained with Mart-1 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells.
图像 2 :
赛默飞世尔 MA5-15237 图像 2
图像 3 :
赛默飞世尔 MA5-15237 图像 3
产品信息
产品类型 :
抗体
产品名称 :
Melan-A Monoclonal Antibody (M2-7C10)
目录# :
MA5-15237
规格 :
500微升
价格 :
美国406.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:100 - 1:200, Immunoprecipitation: 1:50, Western Blot: 1:50 - 1:100
物种 :
人类
克隆 :
M2-7C10
抗体亚型 :
IgG2b, kappa
储存 :
4° C
描述 :
MART1 is involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
免疫原 :
重组hMART-1蛋白
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:100 - 1:200, Immunoprecipitation: 1:50, Western Blot: 1:50 - 1:100
别名 :
A930034P04Rik; Antigen LB39-AA; antigen SK29-AA; MART1; MART-1; melan-A; melanoma antigen recognized by T-cells 1; melanoma associated antigen recognized by T-cells 1; MLANA; Protein Melan-A
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国