产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD31单克隆抗体(2F7B2)
目录 :
MA5-15336
规格 :
100微升
价格 :
美国432.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2F7B2
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 1
图像
图像 1 :
Immunofluorescence analysis of paraffin-embedded human lung cancer(left) and breast cancer(right) cells using CD31 antibody (green). Blue: DRAQ5 fluorescent DNA dye.
图像 2 :
Immunohistochemical analysis of paraffin-embedded human lung cancer (A), lymphonodus tissue (B) and breast cancer (C), showing cytoplasmic localization of vascular endothelial cells using CD31 antibody with DAB staining.
产品信息
产品类型 :
抗体
产品名称 :
CD31单克隆抗体(2F7B2)
目录# :
MA5-15336
规格 :
100微升
价格 :
美国432.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
物种 :
人类
克隆 :
2F7B2
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
免疫原 :
纯化重组片段对应于人CD31在大肠杆菌中表达
格式 :
液体
应用w/稀释 :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
别名 :
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
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公司信息
赛默飞世尔