产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
B-Raf Monoclonal Antibody (1H12)
目录 :
MA5-15495
规格 :
100微升
价格 :
美国466
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1H12
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 1
参考文献
Gillies T, Pargett M, Silva J, Teragawa C, McCormick F, Albeck J. Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway. Mol Syst Biol. 2020;16:e9518 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-15495 图像 1
Confocal immunofluorescence analysis of MCF-7 (left) and HepG2 (right) cells using BRAF antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye
图像 2 :
赛默飞世尔 MA5-15495 图像 2
Immunohistochemical analysis of paraffin-embedded human testis tissues using BRAF antibody.
产品信息
产品类型 :
抗体
产品名称 :
B-Raf Monoclonal Antibody (1H12)
目录# :
MA5-15495
规格 :
100微升
定价 :
美国466
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
物种 :
人类, 小鼠
克隆 :
1H12
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
免疫原 :
纯化重组片段对应于人BRAF在大肠杆菌中表达
格式 :
液体
应用w/稀释 :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
别名 :
94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国