产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SMAD3单克隆抗体(5G11)
目录 :
MA5-15663
规格 :
100微升
价格 :
美国458
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5G11
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
文章摘录数: 6
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Tobar N, Toyos M, Urra C, Méndez N, Arancibia R, Smith P, et al. c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. BMC Cancer. 2014;14:640 pubmed 出版商
  • 免疫印迹; 人类
Tobar N, Avalos M, Méndez N, Smith P, Bernabeu C, Quintanilla M, et al. Soluble MMP-14 produced by bone marrow-derived stromal cells sheds epithelial endoglin modulating the migratory properties of human breast cancer cells. Carcinogenesis. 2014;35:1770-9 pubmed 出版商
Metwally M, Bayoumi A, Khan A, Adams L, Aller R, García Monzón C, et al. Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease. EBioMedicine. 2021;70:103521 pubmed 出版商
Li M, Huang H, Li L, He C, Zhu L, Guo H, et al. Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis. Nat Commun. 2021;12:420 pubmed 出版商
Vervoort S, Lourenço A, Tufegdzic Vidakovic A, Mocholí E, Sandoval J, Rueda O, et al. SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis. Nucleic Acids Res. 2018;46:9578-9590 pubmed 出版商
Li D, Meng L, Xu T, Su Y, Liu X, Zhang Z, et al. RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system. elife. 2017;6: pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-15663 图像 1
Immunofluorescence analysis of NIH/3T3 cells using SMAD3 antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
产品信息
产品类型 :
抗体
产品名称 :
SMAD3单克隆抗体(5G11)
目录# :
MA5-15663
规格 :
100微升
定价 :
美国458
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
物种 :
人类, 小鼠
克隆 :
5G11
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
免疫原 :
纯化重组片段对应于人SMAD3在大肠杆菌中表达
格式 :
液体
应用w/稀释 :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
别名 :
AU022421; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; madh3; madh3a; madh3-A; MGC60396; mMad3; mothers against decapentaplegic homolog 3; mothers against decapentaplegic homolog 3a; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; Smad 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; smad3a; TGF beta response effector Smad3; TGF-beta response effector Smad3; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国