产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Ki67抗原单克隆抗体(8D5)
目录 :
MA5-15690
规格 :
100微升
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
8D5
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 4
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 大鼠; 图 s2
Mehta N, Lyon J, Patil K, Mokarram N, Kim C, Bellamkonda R. Bacterial Carriers for Glioblastoma Therapy. Mol Ther Oncolytics. 2017;4:1-17 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2
Guan C, Zhang J, Zhang J, Shi H, Ni R. Enhanced expression of early mitotic inhibitor-1 predicts a poor prognosis in esophageal squamous cell carcinoma patients. Oncol Lett. 2016;12:114-120 pubmed
  • 免疫印迹; 人类; 图 9c
Tzenaki N, Aivaliotis M, Papakonstanti E. Focal adhesion kinase phosphorylates the phosphatase and tensin homolog deleted on chromosome 10 under the control of p110δ phosphoinositide-3 kinase. FASEB J. 2015;29:4840-52 pubmed 出版商
Kavanagh E, Lindsay S, Halasz M, Gubbins L, Weiner Gorzel K, Guang M, et al. Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells. Oncogenesis. 2017;6:e388 pubmed 出版商
图像
图像 1 :
赛默飞世尔 MA5-15690 图像 1
Immunohistochemical analysis of paraffin-embedded lung cancer (left) and rectal cancer (right) using KI67 antibody with DAB staining.
产品信息
产品类型 :
抗体
产品名称 :
Ki67抗原单克隆抗体(8D5)
目录# :
MA5-15690
规格 :
100微升
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: 1:10,000, Immunocytochemistry: 1:200, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
物种 :
人类
克隆 :
8D5
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
免疫原 :
合成多肽对应于氨基酸(CEDLAGFKELFQTPG)人的KI67, , KLH偶联
格式 :
液体
应用w/稀释 :
ELISA: 1:10,000, Immunocytochemistry: 1:200, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
别名 :
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国