产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Ki67抗原单克隆抗体(8D5)
目录 :
MA5-15690
规格 :
100微升
价格 :
美国489
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
8D5
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
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文章摘录数: 6
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
| Guan C, Zhang J, Zhang J, Shi H, Ni R. Enhanced expression of early mitotic inhibitor-1 predicts a poor prognosis in esophageal squamous cell carcinoma patients. Oncol Lett. 2016;12:114-120 pubmed
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图像
图像 1 :
Immunohistochemical analysis of paraffin-embedded lung cancer (left) and rectal cancer (right) using KI67 antibody with DAB staining.
产品信息
产品类型 :
抗体
产品名称 :
Ki67抗原单克隆抗体(8D5)
目录# :
MA5-15690
规格 :
100微升
定价 :
美国489
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: 1:10,000, Immunocytochemistry: 1:200, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
物种 :
人类
克隆 :
8D5
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
免疫原 :
合成多肽对应于氨基酸(CEDLAGFKELFQTPG)人的KI67, , KLH偶联
格式 :
液体
应用w/稀释 :
ELISA: 1:10,000, Immunocytochemistry: 1:200, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000
别名 :
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
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公司信息
赛默飞世尔