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抗体

蜗牛单克隆抗体(6D2)

MA5-15791

100微升

美国413.00

单克隆

小鼠

未共轭

6D2

免疫印迹, 酶联免疫吸附测定

蜗牛单克隆抗体(6D2)

MA5-15791

100微升

美国413.00

单克隆

小鼠

人类

ELISA: 1:10,000, Western Blot: 1:500-1:2,000

人类

6D2

IgG1

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.

纯化重组片段对应于人snail 1锌指蛋白在大肠杆菌中表达

液体

ELISA: 1:10,000, Western Blot: 1:500-1:2,000

AI194338; dJ710H13.1; Protein sna; protein snail homolog 1; SLUGH2; SNA; Sna protein; Sna1; SNAH; snai; SNAI1; Snail; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1