产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TLR7单克隆抗体(4G6), PE
目录 :
MA5-16249
规格 :
100微升
价格 :
美国453
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
4G6
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 流式细胞仪
更多信息或购买 :
文章摘录数: 2
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
| van Haren S, Dowling D, Foppen W, Christensen D, Andersen P, Reed S, et al. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016;197:4413-4424 pubmed
|
图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
TLR7单克隆抗体(4G6), PE
目录# :
MA5-16249
规格 :
100微升
价格 :
美国453
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: 1 µL per million cells, Western Blot: Assay-Dependent
物种 :
人类, 小鼠
克隆 :
4G6
抗体亚型 :
IgG1, kappa
储存 :
4° C, 不冻结
描述 :
TLR7 is a 10 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain. TLR7 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV). TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8. TLR7 also acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. TLR7 recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.
免疫原 :
Synthetic peptide (277 amino acid ( AA 562- 839)) of TLR7 protein.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µL per million cells, Western Blot: Assay-Dependent
别名 :
RGD1563357; RP23-139P21.3; Tlr7; TLR7-like; toll like receptor 7; toll-like receptor 7; toll-like receptor 7-like; UNQ248/PRO285
更多信息或购买 :
公司信息
赛默飞世尔