产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
B细胞淋巴瘤2相关的X蛋白单克隆抗体(SP47)
目录 :
MA5-16322
规格 :
100微升
价格 :
美国454.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SP47
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 2
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
| Yi X, Wang J, Seol D, Dong Z. Characterization of cell clones stably transfected with short form caspase-9: apoptotic resistance and Bcl-XL expression. Mol Cell Biochem. 2006;282:1-12 pubmed
|
图像
图像 1 :
Immunohistochemical analysis of BAX using anti-BAX Monoclonal Antibody (MA5-16322) in Normal Breast Cancer Tissue. The recommened dilution for this antibody in immunohistochemistry applications is 1:50.
产品信息
产品类型 :
抗体
产品名称 :
B细胞淋巴瘤2相关的X蛋白单克隆抗体(SP47)
目录# :
MA5-16322
规格 :
100微升
价格 :
美国454.00
克隆性 :
单克隆
纯度 :
蛋白质A/G
宿主 :
兔
反应物种 :
人类
应用 :
免疫组化(石蜡): 1:50
物种 :
人类
克隆 :
SP47
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa). BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis. Overexpression of BAX functions to promote cell death. BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.
免疫原 :
合成多肽对应于内部地区人的B细胞淋巴瘤2相关的X蛋白蛋白
格式 :
液体
应用w/稀释 :
免疫组化(石蜡): 1:50
别名 :
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52
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公司信息
赛默飞世尔