产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
突触素单克隆抗体(SP11)
目录 :
MA5-16402
规格 :
500微升
价格 :
美国401.00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SP11
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 45
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 2a
Mu P, Zhang Z, Benelli M, Karthaus W, Hoover E, Chen C, et al. SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. Science. 2017;355:84-88 pubmed 出版商
  • 免疫组化; 人类; 图 4d
De Luca Johnson J, Zenali M. A Previously Undescribed Presentation of Mixed Adenoneuroendocrine Carcinoma. Case Rep Pathol. 2016;2016:9063634 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50
George J, Saito M, Tsuta K, Iwakawa R, Shiraishi K, Scheel A, et al. Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer. Clin Cancer Res. 2017;23:1220-1226 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:50; 表 3
  • 免疫组化-冰冻切片; 小鼠; 1:50; 表 3
Bahia El Idrissi N, Bosch S, Ramaglia V, Aronica E, Baas F, Troost D. Complement activation at the motor end-plates in amyotrophic lateral sclerosis. J Neuroinflammation. 2016;13:72 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 3
Choi S, Chen Z, Tang L, Fang Y, Shin S, Panarelli N, et al. Bcl-xL promotes metastasis independent of its anti-apoptotic activity. Nat Commun. 2016;7:10384 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 1
Böger C, Haag J, Egberts J, Röcken C. Complex APC germline mutation associated metaplasia and intraepithelial neoplasia (CAM-IEN) of the gallbladder. Pathol Res Pract. 2016;212:54-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Projetti F, Serrano E, Vergez S, Bissainthe A, Delisle M, Uro Coste E. Is neuroendocrine differentiation useful to discriminate primary sinonasal intestinal-type adenocarcinomas from metastatic colorectal adenocarcinomas?. J Clin Pathol. 2015;68:79-82 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 s1
Hijioka S, Hosoda W, Mizuno N, Hara K, Imaoka H, Bhatia V, et al. Does the WHO 2010 classification of pancreatic neuroendocrine neoplasms accurately characterize pancreatic neuroendocrine carcinomas?. J Gastroenterol. 2015;50:564-72 pubmed 出版商
  • 免疫组化; 人类; 1:200
Milione M, Gasparini P, Sozzi G, Mazzaferro V, Ferrari A, Casali P, et al. Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation. Histopathology. 2014;64:1014-26 pubmed 出版商
  • 免疫组化; 人类; 1:100
Altinay S, Kusaslan R. Gastrointestinal autonomic nerve tumour of jejunum presenting as a perforated mass. J Pak Med Assoc. 2014;64:461-4 pubmed
  • 免疫组化; 人类; 1:100
Lee J, Yu C, Kim M, Hong S, Lim S, Kim J. Prognostic impact of diagnosing colorectal neuroendocrine carcinoma using the World Health Organization 2010 classification. Surgery. 2014;155:650-8 pubmed 出版商
  • 免疫组化; 人类; 1:100
Chang T, Lin H, Rogers K, Brame L, Yeh M, Yang Q, et al. Expression of aldo-keto reductase family 1 member C3 (AKR1C3) in neuroendocrine tumors & adenocarcinomas of pancreas, gastrointestinal tract, and lung. Int J Clin Exp Pathol. 2013;6:2419-29 pubmed
  • 免疫组化; 人类; 1:100
Hasegawa T, Yamao K, Hijioka S, Bhatia V, Mizuno N, Hara K, et al. Evaluation of Ki-67 index in EUS-FNA specimens for the assessment of malignancy risk in pancreatic neuroendocrine tumors. Endoscopy. 2014;46:32-8 pubmed 出版商
  • 免疫组化; 人类; 1:200
Lopez F, Costales M, Vivanco B, Fresno M, Suarez C, Llorente J. Sinonasal desmoplastic small round cell tumor. Auris Nasus Larynx. 2013;40:573-6 pubmed 出版商
  • 免疫组化; 人类
Thiery Lavenant G, Zavalin A, Caprioli R. Targeted multiplex imaging mass spectrometry in transmission geometry for subcellular spatial resolution. J Am Soc Mass Spectrom. 2013;24:609-14 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫组化; 人类
Mosquera J, Beltran H, Park K, MacDonald T, Robinson B, Tagawa S, et al. Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer. Neoplasia. 2013;15:1-10 pubmed
  • 免疫组化; 人类; 1:100
Masago K, Hosada W, Sasaki E, Murakami Y, Sugano M, Nagasaka T, et al. Is primary pulmonary meningioma a giant form of a meningothelial-like nodule? A case report and review of the literature. Case Rep Oncol. 2012;5:471-8 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Pan J, Yeger H, Ratcliffe P, Bishop T, Cutz E. Hyperplasia of pulmonary neuroepithelial bodies (NEB) in lungs of prolyl hydroxylase -1(PHD-1) deficient mice. Adv Exp Med Biol. 2012;758:149-55 pubmed 出版商
  • 免疫组化; 人类; 1:100
Zhao L, Luo J, Zhang H, Da J. Pigmented paraganglioma of the kidney: a case report. Diagn Pathol. 2012;7:77 pubmed 出版商
  • 免疫组化; 人类; 1:100
Righi L, Rapa I, Votta A, Papotti M, Sapino A. Human achaete-scute homolog-1 expression in neuroendocrine breast carcinoma. Virchows Arch. 2012;460:415-21 pubmed 出版商
  • 免疫组化; 人类
Asioli S, Righi A, de Biase D, Morandi L, Caliendo V, Picciotto F, et al. Expression of p63 is the sole independent marker of aggressiveness in localised (stage I-II) Merkel cell carcinomas. Mod Pathol. 2011;24:1451-61 pubmed 出版商
  • 免疫组化; 人类; 1:100
Lee M, Cho K, Yu C, Park Y, Kim J, Kim J, et al. Perivascular epithelioid cell tumor of the sigmoid colon with transcription factor E3 expression. Ann Diagn Pathol. 2012;16:306-11 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
McCartney S, Vermi W, Lonardi S, Rossini C, Otero K, Calderon B, et al. RNA sensor-induced type I IFN prevents diabetes caused by a ? cell-tropic virus in mice. J Clin Invest. 2011;121:1497-507 pubmed 出版商
  • 免疫组化; 人类
Eloy C, Vinagre J, Cameselle Teijeiro J, Paiva M, Soares P, Sobrinho Simoes M. Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?. Int J Surg Pathol. 2011;19:276-80 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 2, 3, 4
Baydar D, Kulac I, Gurel B, De Marzo A. A case of prostatic adenocarcinoma with aberrant p63 expression: presentation with detailed immunohistochemical study and FISH analysis. Int J Surg Pathol. 2011;19:131-6 pubmed 出版商
  • 免疫组化; 人类; 1:125
Buresh C, Oliai B, Miller R. Reactivity with TdT in Merkel cell carcinoma: a potential diagnostic pitfall. Am J Clin Pathol. 2008;129:894-8 pubmed 出版商
  • 免疫组化; 人类; 1:400
Skalova A, Sima R, Bohus P, Curik R, Lukas J, Michal M. Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): report of two cases with analysis of the VHL gene. Pathol Res Pract. 2008;204:599-606 pubmed 出版商
  • 免疫组化; 人类
Strojan Flezar M, Srebotnik Kirbis I. Identification of carcinoma origin by thyroid transcription factor-1 immunostaining of fine needle aspirates of metastases. Cytopathology. 2009;20:176-82 pubmed 出版商
  • 免疫组化; 人类; 1:100
Eisenthal A, Trejo L, Shtabsky A, Bedny F, Brazowski E. A novel assessment of the quality of immunohistostaining overcomes the limitations of current methods. Pathol Res Pract. 2008;204:323-8 pubmed 出版商
  • 免疫组化; 人类
Asioli S, Accinelli G, Pacchioni D, Bussolati G. Diagnosis of biliary tract lesions by histological sectioning of brush bristles as alternative to cytological smearing. Am J Gastroenterol. 2008;103:1274-81 pubmed 出版商
  • 免疫组化; 人类; 1:100
Asioli S, Righi A, Volante M, Eusebi V, Bussolati G. p63 expression as a new prognostic marker in Merkel cell carcinoma. Cancer. 2007;110:640-7 pubmed
  • 免疫细胞化学; 小鼠
Pan J, Luk C, Kent G, Cutz E, Yeger H. Pulmonary neuroendocrine cells, airway innervation, and smooth muscle are altered in Cftr null mice. Am J Respir Cell Mol Biol. 2006;35:320-6 pubmed
Jensen B, Schuldi M, McAvoy K, Russell K, Boehringer A, Curran B, et al. Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment. EMBO Mol Med. 2020;12:e10722 pubmed 出版商
Yasumizu Y, Rajabi H, Jin C, Hata T, Pitroda S, Long M, et al. MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer. Nat Commun. 2020;11:338 pubmed 出版商
Winter J, Gildea D, Andreas J, Gatti D, Williams K, Lee M, et al. Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer. Cell Syst. 2017;4:31-45.e6 pubmed 出版商
Fuente Martín E, García Cáceres C, Argente Arizón P, Diaz F, Granado M, Freire Regatillo A, et al. Ghrelin Regulates Glucose and Glutamate Transporters in Hypothalamic Astrocytes. Sci Rep. 2016;6:23673 pubmed 出版商
Bolier R, Tolenaars D, Kremer A, Saris J, Pares A, Verheij J, et al. Enteroendocrine cells are a potential source of serum autotaxin in men. Biochim Biophys Acta. 2016;1862:696-704 pubmed 出版商
Terris B, Genevay M, Rouquette A, Audebourg A, Mentha G, Dousset B, et al. Acinar cell carcinoma: a possible diagnosis in patients without intrapancreatic tumour. Dig Liver Dis. 2011;43:971-4 pubmed 出版商
Park S, Park C, Kim S, Jang S, Chi H, Kim M, et al. Detection of bone marrow metastases of neuroblastoma with immunohistochemical staining of CD56, chromogranin A, and synaptophysin. Appl Immunohistochem Mol Morphol. 2010;18:348-52 pubmed 出版商
Yajima N, Mizukami H, Wada R, Saito F, Yagihashi S. Small cell carcinoma with skeletal muscle differentiation of urinary bladder. Pathol Int. 2009;59:748-51 pubmed 出版商
Mouser P, Levy M, Sojka J, Ramos Vara J. Cerebellar abiotrophy in an alpaca (Lama pacos). Vet Pathol. 2009;46:1133-7 pubmed 出版商
Baydar D, Aydin O. Confusing cases: clear cell but not renal cell lesions in kidney. Pathol Int. 2008;58:713-7 pubmed 出版商
Marton E, Feletti A, Basaldella L, Dei Tos A, Bendini M, Longatti P. Atypical cystic meningioma overexpressing AQP1 in early infancy: case report with literature review. Acta Paediatr. 2008;97:1145-9 pubmed 出版商
Wong S, Chan J, Lo E, Chan A, Wong M, Chan C, et al. The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry. Arch Pathol Lab Med. 2007;131:1047-55 pubmed
Volante M, La Rosa S, Castellano I, Finzi G, Capella C, Bussolati G. Clinico-pathological features of a series of 11 oncocytic endocrine tumours of the pancreas. Virchows Arch. 2006;448:545-51 pubmed
图像
图像 1 :
赛默飞世尔 MA5-16402 图像 1
Western blot analysis of Brain Tissue using anti-Synaptophysin Monoclonal Antibody (MA5-16402). The recommened dilution for this antibody in western blot applications is 1:100.
图像 2 :
赛默飞世尔 MA5-16402 图像 2
Immunohistochemical analysis of Synaptophysin using anti-Synaptophysin Monoclonal Antibody (MA5-16402) in Neuroendocrine Cancer Tissue. The recommened dilution for this antibody in immunohistochemistry applications is 1:200.
产品信息
产品类型 :
抗体
产品名称 :
突触素单克隆抗体(SP11)
目录# :
MA5-16402
规格 :
500微升
价格 :
美国401.00
克隆性 :
单克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:200
物种 :
人类, 小鼠, 大鼠
克隆 :
SP11
抗体亚型 :
IgG
储存 :
-20°C or -80°C if preferred
描述 :
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
免疫原 :
合成多肽对应于C末端人的突触素
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:200
别名 :
A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国