产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TGF乙1单克隆抗体(TB21)
目录 :
MA5-16949
规格 :
100微克
价格 :
美国496.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
TB21
反应物种 :
人类, 小鼠, 大鼠, 家羊, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 人类
Bourreau E, Ronet C, Couppie P, Sainte Marie D, Tacchini Cottier F, Launois P. IL-10 producing CD8+ T cells in human infection with Leishmania guyanensis. Microbes Infect. 2007;9:1034-41 pubmed
  • 抑制或激活实验; 人类
Kariminia A, Bourreau E, Pascalis H, Couppie P, Sainte Marie D, Tacchini Cottier F, et al. Transforming growth factor beta 1 production by CD4+ CD25+ regulatory T cells in peripheral blood mononuclear cells from healthy subjects stimulated with Leishmania guyanensis. Infect Immun. 2005;73:5908-14 pubmed
Karagülle O, Yurttas A. Ozone combined with doxorubicin exerts cytotoxic and anticancer effects on Luminal-A subtype human breast cancer cell line. Rev Assoc Med Bras (1992). 2022;68:507-513 pubmed 出版商
Kim B, Kim H, Park J, Cho C, Park S, Lim Y. Restoration of Homeostasis in the Tracheal Mucosa After Thyroid Surgery in a Rat Model. In Vivo. 2022;36:161-169 pubmed 出版商
Zheng X, Li L, Yu C, Yang J, Zhao Y, Su C, et al. Establishment of a tumor immune microenvironment-based molecular classification system of breast cancer for immunotherapy. Aging (Albany NY). 2021;13:24313-24338 pubmed 出版商
Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed 出版商
Jia L, Xue K, Liu J, Habotta O, Hu L, Abdel Moneim A. Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways. Mediators Inflamm. 2020;2020:9419085 pubmed 出版商
Roh S, Kim J, Cha H, Lim H, Park Y, Lee K, et al. Molecular Signatures of Sinus Node Dysfunction Induce Structural Remodeling in the Right Atrial Tissue. Mol Cells. 2020;43:408-418 pubmed 出版商
Kim M, Kim S, Kim H, Hwang C, Man Choi J, Kang H. Development of a reproducible in vivo laser-induced scar model for wound healing study and management. Biomed Opt Express. 2019;10:1965-1977 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
TGF乙1单克隆抗体(TB21)
目录# :
MA5-16949
规格 :
100微克
价格 :
美国496.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
应用 :
ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
物种 :
Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
克隆 :
TB21
抗体亚型 :
IgG1
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
TGF beta-1 (TGFB1, Transforming Growth Factor Beta 1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its pro-domain. Activation of TGF beta-1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF beta-1, an amino-terminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP. TGF beta-1 helps regulates proliferation, differentiation, adhesion, migration in many cell types. Many cells have TGF beta receptors, and the protein positively and negatively regulates many other growth factors. TGF beta-1 is cleaved into a latency-associated peptide and a mature TGF beta-1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGF beta-1 homodimer. The mature peptide may also form heterodimers with other TGF beta family members. The gene for TGF beta-1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease and cystic fibrosis.
免疫原 :
人类转化生长因子β1来自血小板
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
别名 :
CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF ß; TGF ß 1; TGF ß1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFß1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor ß1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国