产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD4单克隆抗体(CT-CD4), PE
目录 :
MA5-17450
规格 :
50微克
价格 :
美国303.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE
克隆名称 :
CT-CD4
反应物种 :
小鼠
应用 :
流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 23
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| |
| de Jersey J, Snelgrove S, Palmer S, Teteris S, Mullbacher A, Miller J, et al. Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2007;104:1295-300 pubmed
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| Cassan C, Piaggio E, Zappulla J, Mars L, Couturier N, Bucciarelli F, et al. Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells. J Immunol. 2006;177:1552-60 pubmed
|
| Fukatsu K, Sakamoto S, Hara E, Ueno C, Maeshima Y, Matsumoto I, et al. Gut ischemia-reperfusion affects gut mucosal immunity: a possible mechanism for infectious complications after severe surgical insults. Crit Care Med. 2006;34:182-7 pubmed
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| Grisaru D, Pick M, Perry C, Sklan E, Almog R, Goldberg I, et al. Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses. J Immunol. 2006;176:27-35 pubmed
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| Koyama K. Dendritic cell expansion occurs in mesenteric lymph nodes of B10.BR mice infected with the murine nematode parasite Trichuris muris. Parasitol Res. 2005;97:186-90 pubmed
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| Mischenko V, Kapina M, Eruslanov E, Kondratieva E, Lyadova I, Young D, et al. Mycobacterial dissemination and cellular responses after 1-lobe restricted tuberculosis infection of genetically susceptible and resistant mice. J Infect Dis. 2004;190:2137-45 pubmed
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| Zheng S, Jiang J, Shen H, Chen Y. Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice. J Immunol. 2004;173:5652-8 pubmed
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| Cabarrocas J, Piaggio E, Zappulla J, Desbois S, Mars L, Lassmann H, et al. A transgenic mouse model for T-cell ignorance of a glial autoantigen. J Autoimmun. 2004;22:179-89 pubmed
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| Chen B, Cui X, Sempowski G, Domen J, Chao N. Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation. Blood. 2004;103:4344-52 pubmed
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| Eruslanov E, Majorov K, Orlova M, Mischenko V, Kondratieva T, Apt A, et al. Lung cell responses to M. tuberculosis in genetically susceptible and resistant mice following intratracheal challenge. Clin Exp Immunol. 2004;135:19-28 pubmed
|
| Koyama K. NK1.1+ cell depletion in vivo fails to prevent protection against infection with the murine nematode parasite Trichuris muris. Parasite Immunol. 2002;24:527-33 pubmed
|
| Egan P, Lawlor K, Alexander W, Wicks I. Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation. J Clin Invest. 2003;111:915-24 pubmed
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| Carter R, Campbell I, O Donnel K, Wicks I. Vascular cell adhesion molecule-1 (VCAM-1) blockade in collagen-induced arthritis reduces joint involvement and alters B cell trafficking. Clin Exp Immunol. 2002;128:44-51 pubmed
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| Campbell I, O DONNELL K, Lawlor K, Wicks I. Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. J Clin Invest. 2001;107:1519-27 pubmed
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| Izeradjene K, Revillard J, Genestier L. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells. Int Immunol. 2001;13:85-93 pubmed
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| Chen B, Liu C, Cui X, Fidler J, Chao N. Prevention of graft-versus-host disease by a novel immunosuppressant, PG490-88, through inhibition of alloreactive T cell expansion. Transplantation. 2000;70:1442-7 pubmed
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| Martin P, del Hoyo G, Anjuere F, Ruiz S, Arias C, Marín A, et al. Concept of lymphoid versus myeloid dendritic cell lineages revisited: both CD8alpha(-) and CD8alpha(+) dendritic cells are generated from CD4(low) lymphoid-committed precursors. Blood. 2000;96:2511-9 pubmed
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| Anjuere F, del Hoyo G, Martin P, Ardavin C. Langerhans cells develop from a lymphoid-committed precursor. Blood. 2000;96:1633-7 pubmed
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| Lepault F, Gagnerault M. Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice. J Immunol. 2000;164:240-7 pubmed
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| Dejbakhsh Jones S, Strober S. Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow. Proc Natl Acad Sci U S A. 1999;96:14493-8 pubmed
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| Pan L, Sato S, Frederick J, Sun X, Zhuang Y. Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol. 1999;19:5969-80 pubmed
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| Samoilova E, Horton J, Hilliard B, Liu T, Chen Y. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J Immunol. 1998;161:6480-6 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD4单克隆抗体(CT-CD4), PE
目录# :
MA5-17450
规格 :
50微克
价格 :
美国303.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 1.0 µg/1x10^6 cells
物种 :
小鼠
克隆 :
CT-CD4
抗体亚型 :
IgG2a
储存 :
4° C, 不冻结
描述 :
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
免疫原 :
CD4(L3/T4)抗原
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1.0 µg/1x10^6 cells
别名 :
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
更多信息或购买 :
公司信息
赛默飞世尔