产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD25单克隆抗体(PC61.5。 3), PE
目录 :
MA5-17818
规格 :
300微克
价格 :
美国472.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE
克隆名称 :
PC61.5。 3
反应物种 :
小鼠
应用 :
流式细胞仪, 免疫组化-冰冻切片, 其他
更多信息或购买 :
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 1b
Kim M, Borcherding N, Ahmed K, Voigt A, Vishwakarma A, Kolb R, et al. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nat Commun. 2021;12:5764 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6a
Fu Y, Ding Y, Wang Q, Zhu F, Tan Y, Lu X, et al. Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2. Sci Adv. 2020;6:eaay9269 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 4d
Rosenbaum M, Gewies A, Pechloff K, Heuser C, Engleitner T, Gehring T, et al. Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells. Nat Commun. 2019;10:2352 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 1a
Chorro L, Suzuki M, Chin S, Williams T, Snapp E, Odagiu L, et al. Interleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape. Nat Commun. 2018;9:5368 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1h
Gaddis D, Padgett L, Wu R, McSkimming C, Romines V, Taylor A, et al. Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. Nat Commun. 2018;9:1095 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2b
Lamprianou S, Gysemans C, Bou Saab J, Pontes H, Mathieu C, Meda P. Glibenclamide Prevents Diabetes in NOD Mice. PLoS ONE. 2016;11:e0168839 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Goldstein J, Burlion A, Zaragoza B, Sendeyo K, Polansky J, Huehn J, et al. Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression. PLoS ONE. 2016;11:e0153682 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Redpath S, Van Der Werf N, Cervera A, MacDonald A, Gray D, Maizels R, et al. ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection. Eur J Immunol. 2013;43:705-15 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Barwig C, Raker V, Montermann E, Grabbe S, Reske Kunz A, Sudowe S. Antigen dose-dependent suppression of murine IgE responses is mediated by CD4(-)CD8(-) double-negative T cells. Clin Exp Allergy. 2010;40:891-901 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Fahl S, Crittenden R, Allman D, Bender T. c-Myb is required for pro-B cell differentiation. J Immunol. 2009;183:5582-92 pubmed 出版商
  • 流式细胞仪; 小鼠
Walsh C, Smith P, Fallon P. Role for CTLA-4 but not CD25+ T cells during Schistosoma mansoni infection of mice. Parasite Immunol. 2007;29:293-308 pubmed
  • 流式细胞仪; 小鼠
Cassan C, Piaggio E, Zappulla J, Mars L, Couturier N, Bucciarelli F, et al. Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells. J Immunol. 2006;177:1552-60 pubmed
  • 流式细胞仪; 小鼠
Sfondrini L, Rossini A, Besusso D, Merlo A, Tagliabue E, Menard S, et al. Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer. J Immunol. 2006;176:6624-30 pubmed
  • 流式细胞仪; 小鼠
Sangaletti S, Gioiosa L, Guiducci C, Rotta G, Rescigno M, Stoppacciaro A, et al. Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice. J Cell Sci. 2005;118:3685-94 pubmed
  • 流式细胞仪; 小鼠
Gray P, Arimilli S, Palmer E, Parks G, Alexander Miller M. Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract. J Virol. 2005;79:3339-49 pubmed
  • 流式细胞仪; 小鼠; 图 3
Mangan N, Fallon R, Smith P, Van Rooijen N, McKenzie A, Fallon P. Helminth infection protects mice from anaphylaxis via IL-10-producing B cells. J Immunol. 2004;173:6346-56 pubmed
  • 流式细胞仪; 小鼠; 表 1
Kawamoto H, Ohmura K, Fujimoto S, Lu M, Ikawa T, Katsura Y. Extensive proliferation of T cell lineage-restricted progenitors in the thymus: an essential process for clonal expression of diverse T cell receptor beta chains. Eur J Immunol. 2003;33:606-15 pubmed
  • 流式细胞仪; 小鼠; 图 2
Cabatingan M, Schmidt M, Sen R, Woodland R. Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit. J Immunol. 2002;169:6795-805 pubmed
  • 流式细胞仪; 小鼠
Angulo I, Jiménez Díaz M, García Bustos J, Gargallo D, de las Heras F, Muñoz Fernández M, et al. Candida albicans infection enhances immunosuppression induced by cyclophosphamide by selective priming of suppressive myeloid progenitors for NO production. Cell Immunol. 2002;218:46-58 pubmed
  • 流式细胞仪; 小鼠; 图 8
Goñi O, Alcaide P, Fresno M. Immunosuppression during acute Trypanosoma cruzi infection: involvement of Ly6G (Gr1(+))CD11b(+ )immature myeloid suppressor cells. Int Immunol. 2002;14:1125-34 pubmed
  • 流式细胞仪; 小鼠; 图 4, 5
Wu T, Lee J, Lai Y, Hsu J, Tsai C, Lee Y, et al. Reduced expression of Bcl-2 in CD8+ T cells deficient in the IL-15 receptor alpha-chain. J Immunol. 2002;168:705-12 pubmed
  • 流式细胞仪; 小鼠
Kovalev G, Franklin D, Coffield V, Xiong Y, Su L. An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. J Immunol. 2001;167:3285-92 pubmed
  • 流式细胞仪; 小鼠
Campbell I, O DONNELL K, Lawlor K, Wicks I. Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. J Clin Invest. 2001;107:1519-27 pubmed
  • 流式细胞仪; 小鼠; 图 2
Attinger A, MacDonald H, Acha Orbea H. Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency. Eur J Immunol. 2001;31:884-93 pubmed
  • 流式细胞仪; 小鼠; 图 3
Izeradjene K, Revillard J, Genestier L. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells. Int Immunol. 2001;13:85-93 pubmed
  • 流式细胞仪; 小鼠
Kang J, Coles M, Raulet D. Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes. J Exp Med. 1999;190:973-82 pubmed
  • 流式细胞仪; 小鼠
Payne K, Medina K, Kincade P. Loss of c-kit accompanies B-lineage commitment and acquisition of CD45R by most murine B-lymphocyte precursors. Blood. 1999;94:713-23 pubmed
  • 流式细胞仪; 小鼠
Spiekermann G, Nagler Anderson C. Oral administration of the bacterial superantigen staphylococcal enterotoxin B induces activation and cytokine production by T cells in murine gut-associated lymphoid tissue. J Immunol. 1998;161:5825-31 pubmed
  • 流式细胞仪; 小鼠
Liu L, Rich B, Inobe J, Chen W, Weiner H. Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4. Int Immunol. 1998;10:1017-26 pubmed
  • 流式细胞仪; 小鼠
van Meerwijk J, Marguerat S, MacDonald H. Homeostasis limits the development of mature CD8+ but not CD4+ thymocytes. J Immunol. 1998;160:2730-4 pubmed
  • 流式细胞仪; 小鼠; 图 2
Aiba Y, Hirayama F, Ogawa M. Clonal proliferation and cytokine requirement of murine progenitors for natural killer cells. Blood. 1997;89:4005-12 pubmed
  • 流式细胞仪; 小鼠; 图 2
Lowenthal J, Zubler R, Nabholz M, MacDonald H. Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Nature. 1985;315:669-72 pubmed
  • 其他; 小鼠; 图 1
  • 免疫组化-冰冻切片; 小鼠; 图 3
Ceredig R, Lowenthal J, Nabholz M, MacDonald H. Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Nature. 1985;314:98-100 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD25单克隆抗体(PC61.5。 3), PE
目录# :
MA5-17818
规格 :
300微克
价格 :
美国472.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/1x10^6 cells
物种 :
小鼠
克隆 :
PC61.5。 3
抗体亚型 :
IgG1
储存 :
4° C, 不冻结
描述 :
CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2 plays an important role as a growth factor, differentiation factor, and regulator of cell death. IL-2 stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocyte macrophage colony formation. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
免疫原 :
B6.1 CTL细胞株
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/1x10^6 cells
别名 :
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国