产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD44单克隆抗体(IM7.8。 1)
目录 :
MA5-17875
规格 :
200微克
价格 :
美国358.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
IM7.8。 1
反应物种 :
小鼠, 猫
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 27
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 猫; 图 2
Parys M, Nelson N, Koehl K, Miller R, Kaneene J, Kruger J, et al. Safety of Intraperitoneal Injection of Adipose Tissue-Derived Autologous Mesenchymal Stem Cells in Cats. J Vet Intern Med. 2016;30:157-63 pubmed 出版商
  • 流式细胞仪; 小鼠
Yassai M, Cooley B, Gorski J. Developmental dynamics of post-selection thymic DN iNKT. PLoS ONE. 2012;7:e43509 pubmed 出版商
  • 流式细胞仪; 小鼠
Zaragoza B, Evaristo C, Kissenpfennig A, Libri V, Malissen B, Rocha B, et al. Cell-to-cell interactions and signals involved in the reconstitution of peripheral CD8 T(CM) and T(EM) cell pools. PLoS ONE. 2011;6:e17423 pubmed 出版商
  • 流式细胞仪; 小鼠; 表 1
Echeverry A, Saijo S, Schesser K, Adkins B. Yersinia enterocolitica promotes robust mucosal inflammatory T-cell immunity in murine neonates. Infect Immun. 2010;78:3595-608 pubmed 出版商
  • 流式细胞仪; 小鼠
Tsumiyama K, Miyazaki Y, Shiozawa S. Self-organized criticality theory of autoimmunity. PLoS ONE. 2009;4:e8382 pubmed 出版商
  • 流式细胞仪; 小鼠
Getahun A, Heyman B. Studies on the mechanism by which antigen-specific IgG suppresses primary antibody responses: evidence for epitope masking and decreased localization of antigen in the spleen. Scand J Immunol. 2009;70:277-87 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Kanwar N, Fayyazi A, Backofen B, Nitsche M, Dressel R, von Mollard G. Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin. Cell Tissue Res. 2008;334:227-42 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Wells J, Cowled C, Farzaneh F, Noble A. Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. J Immunol. 2008;181:3422-31 pubmed
  • 流式细胞仪; 小鼠
Rana S, Byrne S, MacDonald L, Chan C, Halliday G. Ultraviolet B suppresses immunity by inhibiting effector and memory T cells. Am J Pathol. 2008;172:993-1004 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
King S, Knorn A, Ohnmacht C, Voehringer D. Accumulation of effector CD4 T cells during type 2 immune responses is negatively regulated by Stat6. J Immunol. 2008;180:754-63 pubmed
  • 流式细胞仪; 小鼠
Hintzen G, Ohl L, del Rio M, Rodriguez Barbosa J, Pabst O, Kocks J, et al. Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node. J Immunol. 2006;177:7346-54 pubmed
  • 流式细胞仪; 小鼠
Getahun A, Hjelm F, Heyman B. IgE enhances antibody and T cell responses in vivo via CD23+ B cells. J Immunol. 2005;175:1473-82 pubmed
  • 流式细胞仪; 小鼠; 图 3
Kelchtermans H, De Klerck B, Mitera T, Van Balen M, Bullens D, Billiau A, et al. Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma. Arthritis Res Ther. 2005;7:R402-15 pubmed
  • 流式细胞仪; 小鼠; 图 2
Maris C, Miller J, Altman J, Jacob J. A transgenic mouse model genetically tags all activated CD8 T cells. J Immunol. 2003;171:2393-401 pubmed
  • 流式细胞仪; 小鼠
Noble A, Leggat J, Inderberg E. CD8+ immunoregulatory cells in the graft-versus-host reaction: CD8 T cells activate dendritic cells to secrete interleukin-12/interleukin-18 and induce T helper 1 autoantibody. Immunology. 2003;109:476-86 pubmed
  • 流式细胞仪; 小鼠
Liu L, Rich B, Inobe J, Chen W, Weiner H. Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4. Int Immunol. 1998;10:1017-26 pubmed
  • 流式细胞仪; 小鼠; 图 1
Sato S, Steeber D, Jansen P, Tedder T. CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19. J Immunol. 1997;158:4662-9 pubmed
  • 流式细胞仪; 小鼠; 表 1
Lin K, Abraham K. Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway. Int Immunol. 1997;9:291-306 pubmed
Johnstone C, Tu Y, Langenbach S, Baloyan D, Pattison A, Lock P, et al. Annexin A1 Is Required for Efficient Tumor Initiation and Cancer Stem Cell Maintenance in a Model of Human Breast Cancer. Cancers (Basel). 2021;13: pubmed 出版商
Carlow D, Tra M, Ziltener H. A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin. PLoS ONE. 2018;13:e0205685 pubmed 出版商
Jain R, Sheridan J, Policheni A, Heinlein M, Gandolfo L, Dewson G, et al. A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice. Blood. 2017;130:2504-2515 pubmed 出版商
Forsberg M, Ciecko A, Bednar K, Itoh A, Kachapati K, Ridgway W, et al. CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. J Immunol. 2017;198:3857-3868 pubmed 出版商
Li Y, Lu Y, Wang S, Han Z, Zhu F, Ni Y, et al. USP21 prevents the generation of T-helper-1-like Treg cells. Nat Commun. 2016;7:13559 pubmed 出版商
Besseyrias V, Fiorini E, Strobl L, Zimber Strobl U, Dumortier A, Koch U, et al. Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med. 2007;204:331-43 pubmed
Fisson S, Darrasse Jèze G, Litvinova E, Septier F, Klatzmann D, Liblau R, et al. Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J Exp Med. 2003;198:737-46 pubmed
Almeida A, Borghans J, Freitas A. T cell homeostasis: thymus regeneration and peripheral T cell restoration in mice with a reduced fraction of competent precursors. J Exp Med. 2001;194:591-9 pubmed
Roach D, Briscoe H, Saunders B, France M, Riminton S, Britton W. Secreted lymphotoxin-alpha is essential for the control of an intracellular bacterial infection. J Exp Med. 2001;193:239-46 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD44单克隆抗体(IM7.8。 1)
目录# :
MA5-17875
规格 :
200微克
价格 :
美国358.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
小鼠
应用 :
ELISA: Assay-dependent, Flow Cytometry: 0.2 µg/1x10^6 cells, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
物种 :
小鼠
克隆 :
IM7.8。 1
抗体亚型 :
IgG2b
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. CD44 is expressed by hematopoietic, non-hematopoietic cells, epithelial tissues, and to filopodia in cultured keratinocytes. Further, bone marrow myeloid cells and memory T cells express CD44 at high levels, and peripheral B and T cells can upregulate the expression of CD44 in response to certain stimulatory events. Transcripts for the CD44 gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full-length nature of some of these variants have not been determined. Alternative splicing is the basis for the structural and functional diversity of the CD44 protein. Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus. CD44 also may be related to tumor metastasis formation.
免疫原 :
小鼠CD44
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: 0.2 µg/1x10^6 cells, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
别名 :
AU023126; AW121933; AW146109; Bovine CD44; CD44; CD44 antigen; CD44 antigen-like protein; CD44 molecule; CD44 molecule (Indian blood group); CD44 protein; CD44 variant; CD44A; CD44-like protein; CDW44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); cell-surface glycoprotein; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; Epican; extracellular matrix receptor III; extracellular matrix receptor-III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronan receptor; Hyaluronate receptor; IN; LHR; Ly-24; lymphocyte antigen 24; lymphocyte surface antigen precursor CD44; MC56; MDU2; MDU3; METAA; MIC4; PGP I; Pgp1; PGP-1; PGPI; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; putative Bos taurus CD44; RHAMM; sCD 44; sCD44; soluble CD 44; soluble CD44
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国