产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD45RB单克隆抗体(16A), PE
目录 :
MA5-17886
规格 :
50微克
价格 :
美国183.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE
克隆名称 :
16A
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 1
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Nakayama T, Kasprowicz D, Yamashita M, Schubert L, Gillard G, Kimura M, et al. The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression. J Immunol. 2002;168:87-94 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
CD45RB单克隆抗体(16A), PE
目录# :
MA5-17886
规格 :
50微克
价格 :
美国183.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/1x10^6 cells
物种 :
小鼠
克隆 :
16A
抗体亚型 :
IgG2a
储存 :
4° C, 不冻结
描述 :
CD45RB is a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed in microglia and inflammatory cells. In addition to involvement in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is involved in DNA fragmentation during apoptosis. CD45 is expressed on cells of the human hematopoietic lineage with the exception of mature red cells.
免疫原 :
TH2 cell clones, final boost with TH2 clone D10 Fusion Partner: Ag8.653
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/1x10^6 cells
别名 :
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; Leukocyte common antigen; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen
更多信息或购买 :
公司信息
赛默飞世尔