产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
UCH37单克隆抗体(854CT5.5。 6)
目录 :
MA5-18114
规格 :
400微升
价格 :
美国436
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
854CT5.5。 6
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
UCH37单克隆抗体(854CT5.5。 6)
目录# :
MA5-18114
规格 :
400微升
价格 :
美国436
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
Western Blot: 1:1000
物种 :
人类
克隆 :
854CT5.5。 6
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
UCH-L5 (ubiquitin carboxyl-terminal hydrolase isozyme L5), also known as UCH37, is a 329 amino acid protein that functions to edit polyubiquinated protein substrates. Since UCH-L5 has the potential to rescue ubiquinated proteins, including oncogenic proteins, from proteasomal degradation, it is likely that deregulation of UCH-L5 may affect tumor growth. Through associations with Smad7, UHC-L5 can dramatically upregulate TGF -dependent gene expression by de-ubiquinating and stabilizing TGF RI. Also, since overexpression of UCH-L5 and other deubiquitinating enzymes has been observed in many cancer cell lines, inhibition of these proteins may be of some interest in designing therapies for cancer treatment. There are four isoforms of UCH-L5 that exist as a result of alternative splicing events.
免疫原 :
纯化多聚组氨酸标签UCH37蛋白
格式 :
液体
应用w/稀释 :
Western Blot: 1:1000
别名 :
5830413B11Rik; AD-019; CGI-70; INO80 complex subunit R; INO80R; ubiquitin carboxyl-terminal esterase L5; Ubiquitin carboxyl-terminal hydrolase isozyme L5; ubiquitin carboxyl-terminal hydrolase L5; ubiquitin C-terminal hydrolase 37; ubiquitin C-terminal hydrolase L5; ubiquitin C-terminal hydrolase UCH37; ubiquitin thioesterase L5; Uch37; Uchl5; UCH-L5
更多信息或购买 :
公司信息
赛默飞世尔