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抗体

Langerin Monoclonal Antibody (343828), APC

MA5-23530

100试验

美国219.00

单克隆

小鼠

APC

343828

Langerin Monoclonal Antibody (343828), APC

MA5-23530

100试验

美国219.00

单克隆

蛋白质A/G

小鼠

人类

Flow Cytometry: 10 µL/1x10^6 cells

人类

343828

IgG1

4° C, store in dark, DO NOT FREEZE!

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Mouse myeloma cell line NS0-derived recombinant human Langerin/CD207 Tyr64-Pro328

液体

Flow Cytometry: 10 µL/1x10^6 cells

CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913