产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NLRP3单克隆抗体(768319)
目录 :
MA5-23919
规格 :
100微克
价格 :
美国396.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
768319
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 4
参考文献
Silva D, Candeias E, Esteves A, Magalhães J, Ferreira I, Nunes Costa D, et al. Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons. J Neuroinflammation. 2020;17:332 pubmed 出版商
Huang J, Gandini M, Chen L, M Dahoma S, Stemkowski P, Chung H, et al. Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk. Cell Rep. 2020;33:108233 pubmed 出版商
Yoon J, Lee H, Kim H, Han B, Lee H, Lee Y, et al. Sauchinone Protects Renal Mesangial Cell Dysfunction against Angiotensin II by Improving Renal Fibrosis and Inflammation. Int J Mol Sci. 2020;21: pubmed 出版商
He X, Zeng Y, Li G, Feng Y, Wu C, Liang F, et al. Extracellular ASC exacerbated the recurrent ischemic stroke in an NLRP3-dependent manner. J Cereb Blood Flow Metab. 2020;40:1048-1060 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
NLRP3单克隆抗体(768319)
目录# :
MA5-23919
规格 :
100微克
价格 :
美国396.00
克隆性 :
单克隆
纯度 :
蛋白质A/G
宿主 :
大鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: 2.5 µg/1x10^6 cells, Immunocytochemistry: 8-25 µg/mL, Western Blot: 2 µg/mL
物种 :
人类, 小鼠
克隆 :
768319
抗体亚型 :
IgG2a
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site domain, and a leucine-rich repeat motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome, and neonatal-onset multisystem inflammatory disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
免疫原 :
E. coli-derived recombinant mouse NLRP3/NALP3 Met1-Arg153
格式 :
冻干
应用w/稀释 :
Flow Cytometry: 2.5 µg/1x10^6 cells, Immunocytochemistry: 8-25 µg/mL, Western Blot: 2 µg/mL
别名 :
AGTAVPRL; AII; AII/AVP; Angiotensin/vasopressin receptor AII/AVP-like; AVP; C1orf7; caterpiller protein 1.1; Cias1; CLR1.1; cold autoinflammatory syndrome 1 homolog; cold autoinflammatory syndrome 1 protein; cold autoinflammatory syndrome 1 protein homolog; Cold-induced autoinflammatory syndrome 1 protein; cryopyrin; FCAS; FCAS1; FCU; FLJ95925; mast cell maturation inducible protein 1; mast cell maturation-associated-inducible protein 1; Mmig1; MWS; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; NACHT, LRR and PYD containing protein 3; NACHT, LRR and PYD domains-containing protein 3; NACHT/LRR/pyrin domain-containing protein 3; NALP3; NLR family pyrin domain containing 3; NLR family, pyrin domain containing 3; Nlrp3; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; PYPAF1; PYRIN-containing APAF1-like protein 1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国