产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
B-Raf (V600E) Recombinant Rabbit Monoclonal Antibody (RM8)
目录 :
MA5-24661
规格 :
100微克
价格 :
美国450.00
克隆性 :
重组
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
RM8
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 3
| 参考文献 |
|---|
产品信息
产品类型 :
抗体
产品名称 :
B-Raf (V600E) Recombinant Rabbit Monoclonal Antibody (RM8)
目录# :
MA5-24661
规格 :
100微克
价格 :
美国450.00
克隆性 :
重组单克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
人类
应用 :
ELISA: 0.5-2 µg/mL, Immunocytochemistry: 0.5-5 µg/mL, Immunohistochemistry: 0.5-5 µg/mL, Western Blot: 0.5-2 µg/mL
物种 :
人类
克隆 :
RM8
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
This gene, B-RAF/BRAF, encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome.
免疫原 :
Peptide corresponding to B-Raf V600E mutant.
格式 :
液体
应用w/稀释 :
ELISA: 0.5-2 µg/mL, Immunocytochemistry: 0.5-5 µg/mL, Immunohistochemistry: 0.5-5 µg/mL, Western Blot: 0.5-2 µg/mL
更多信息或购买 :
公司信息
赛默飞世尔