产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲单克隆抗体(VPM61)
目录 :
MA5-28513
规格 :
100µg
价格 :
美国272
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
VPM61
反应物种 :
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲单克隆抗体(VPM61)
目录# :
MA5-28513
规格 :
100µg
价格 :
美国272
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Ovine
应用 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
物种 :
Ovine
克隆 :
VPM61
抗体亚型 :
IgG2a
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
免疫原 :
Recombinant ovine TNF alpha
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国