产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
JNK3重组兔单克隆抗体(SD082-09)
目录 :
MA5-32387
规格 :
100微升
价格 :
美国446.00
克隆性 :
重组
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SD082-09
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
JNK3重组兔单克隆抗体(SD082-09)
目录# :
MA5-32387
规格 :
100微升
价格 :
美国446.00
克隆性 :
重组单克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100-1:500, Western Blot: 1:500
物种 :
人类, 小鼠, 大鼠
克隆 :
SD082-09
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (NhpK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
免疫原 :
Synthetic peptide within Human JNK3 aa 401-450
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100-1:500, Western Blot: 1:500
别名 :
C230008H04Rik; c-Jun N-terminal kinase 3; hypothetical protein LOC569698; jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10; mitogen activated protein kinase 10; mitogen-activated protein kinase 10; OTTHUMP00000161181; OTTHUMP00000161183; OTTHUMP00000218718; p493F12; p54-beta; p54bSAPK; PRKM10; SAPb; SAPK(beta); SAPK/Erk/kinase 2; SAPK1B; SAPK-beta; SAPKC; Serk2; Stress activated protein kinase beta; stress-activated protein kinase 1b; Stress-activated protein kinase JNK3; zgc:123234
更多信息或购买 :
公司信息
赛默飞世尔