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抗体

PTP1B重组兔单克隆抗体(JJ0935)

MA5-32488

100微升

美国446.00

重组

domestic rabbit

未共轭

JJ0935

人类, 斑马鱼

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

PTP1B重组兔单克隆抗体(JJ0935)

MA5-32488

100微升

美国446.00

重组单克隆

蛋白质A

兔

人类, 斑马鱼

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100-1:500, Immunohistochemistry: 1:50-1:200, Western Blot: 1:1,000-1:2,000

人类, 斑马鱼

JJ0935

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

Synthetic peptide within Human PTP1B aa 374-400

液体

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100-1:500, Immunohistochemistry: 1:50-1:200, Western Blot: 1:1,000-1:2,000

CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03