NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

ALDH3A2单克隆抗体(7F2)

MA5-32933

100微升

美国460

单克隆

小鼠

未共轭

7F2

ALDH3A2单克隆抗体(7F2)

MA5-32933

100微升

美国460

单克隆

亲和色谱

小鼠

人类

Western Blot: 1:1000

人类

7F2

IgG2a

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.

重组全长人类ALDH3A2

液体

Western Blot: 1:1000

Ahd3; Ahd-3; Ahd-3r; Ahd3-r; AI194803; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase 10; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family member A2; aldehyde dehydrogenase 3 family, member A2; aldehyde dehydrogenase 3A2; aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; aldehyde dehydrogenase family 3, subfamily A2; ALDH10; Aldh3; Aldh3a2; Aldh4; Aldh4-r; DKFZp686E23276; FALDH; Fatty aldehyde dehydrogenase; FLJ20851; LOC100688308; Microsomal aldehyde dehydrogenase; msALDH; multidrug and toxin extrusion protein 2-like; SLS