产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TAB1单克隆抗体(2G4)
目录 :
MA5-32953
规格 :
100微升
价格 :
美国460
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2G4
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
TAB1单克隆抗体(2G4)
目录# :
MA5-32953
规格 :
100微升
价格 :
美国460
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Western Blot: 1:1000
物种 :
人类
克隆 :
2G4
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (TAB1) is a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. TAB1 interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. It can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli.
免疫原 :
Synthetic peptide, corresponding to the N-terminus of Human TAB1.
格式 :
液体
应用w/稀释 :
Western Blot: 1:1000
别名 :
2310012M03Rik; 3'-Tab1; b2b449Clo; beta activated kinase-1 binding protein-1; MAP3K7IP1; MGC57664; mitogen activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7 interacting protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; RP3-407F17.2; Tab1; TAB1beta; Tak1-binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; transforming growth factor beta-activated kinase-binding protein 1
更多信息或购买 :
公司信息
赛默飞世尔