NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

ZO-1重组兔单克隆抗体(BLR092G)

MA5-44376

10微升

美国135.00

重组

domestic rabbit

未共轭

BLR092G

人类, 小鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片

ZO-1重组兔单克隆抗体(BLR092G)

MA5-44376

10微升

美国135.00

重组单克隆

纯化

兔

人类, 小鼠

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 12 µL/1 mg lysate, Western Blot: 1:1,000

人类, 小鼠

BLR092G

IgG

2-8°C

ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.

Immunogen was a peptide representing a region between residue 650 and 700 of human tight junction protein ZO-1.

液体

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: 12 µL/1 mg lysate, Western Blot: 1:1,000

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1