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抗体

CaMKII甲单克隆抗体(6G9), APC

MA5-45143

100微克

美国385.00

单克隆

小鼠

APC

6G9

人类, 小鼠, 大鼠, 牛

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片

CaMKII甲单克隆抗体(6G9), APC

MA5-45143

100微克

美国385.00

单克隆

蛋白质G

小鼠

牛, 人类, 小鼠, 大鼠

ELISA: Assay-dependent, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry (PFA fixed): 1:2,000-1:10,000, Immunoprecipitation: Assay-dependent, Radioimmune assays: Assay-dependent, Western Blot: 1:10,000

牛, 人类, 小鼠, 大鼠

6G9

IgG1

4° C

CAMK2A (CaMKII alpha) is a serine/threonine kinase that regulates a number of cellular functions including neuronal processes, gene expression, carbohydrate metabolism, cytoskeletal function, and calcium homeostatsis. Autophosphorylation of threonine 286 in the presence of Ca2+ and calmodulin activates CAMK2A with the ability to switch from calmodulin-dependent to a calmodulin independent activity. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+/calmodulin (CaM) binding and autophosphorylation and has been implicated in regulation of the cell cycle and transcription. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.

Partially purified rat CaMKII

液体

ELISA: Assay-dependent, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry (PFA fixed): 1:2,000-1:10,000, Immunoprecipitation: Assay-dependent, Radioimmune assays: Assay-dependent, Western Blot: 1:10,000

alpha CaM kinase II; alpha-CaMKII; Ca2+/calmodulin-dependent protein kinase II; Ca2+/calmodulin-dependent protein kinase II alpha; Calci; calcium/calmodulin dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II alpha subunit; caM kinase II subunit alpha; CaMK II; CAMK2; Camk2a; CAMKA; CaMKII; CaMK-II alpha subunit; caMK-II subunit alpha; CaMKIINalpha; CaM-kinase II alpha chain; EC 2.7.11.17; KIAA0968; mKIAA0968; OTTHUMP00000165787; OTTHUMP00000165788; Phospho-CaMKI; PK2CDD; PKCCD; R74975