产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
粘着斑蛋白重组兔单克隆抗体(HL1873)
目录 :
MA5-47210
规格 :
100微升
价格 :
美国416.00
克隆性 :
重组
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
HL1873
反应物种 :
人类, 小鼠, 大鼠, 犬, 斑马鱼, 猫
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
粘着斑蛋白重组兔单克隆抗体(HL1873)
目录# :
MA5-47210
规格 :
100微升
价格 :
美国416.00
克隆性 :
重组单克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
狗, 猫, 人类, 小鼠, 大鼠, 斑马鱼
应用 :
Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:3,000
物种 :
狗, 猫, 人类, 小鼠, 大鼠, 斑马鱼
克隆 :
HL1873
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the membrane. It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques. In the assembly of adhesion plaques, the beta subunit of integrin binds to talin. Talin binds to vinculin that interacts with alpha-actinin and possibly with itself. Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system. Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.
免疫原 :
Recombinant protein encompassing a sequence within the N-terminus region of human Vinculin. The exact sequence is proprietary.
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500-1:3,000
别名 :
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
更多信息或购买 :
公司信息
赛默飞世尔