产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ICAM-1单克隆抗体(1A29)
目录 :
MA5407
规格 :
500微克
价格 :
美国450.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1A29
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪
更多信息或购买 :
文章摘录数: 23
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠
Bedirli N, Akyurek N, Kurtipek O, Kavutcu M, Kartal S, Bayraktar A. Thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion. Anesth Analg. 2011;113:1226-32 pubmed 出版商
  • 免疫组化; 大鼠; 1:50; 图 3
  • 免疫印迹; 大鼠; 1:50; 图 5
Ito T, Kumamoto T, Horinouchi H, Yukishige K, Sugihara R, Fujimoto S, et al. Adhesion molecule expression in experimental myositis. Muscle Nerve. 2002;25:409-18 pubmed
Sifat A, Archie S, Nozohouri S, Villalba H, Zhang Y, Sharma S, et al. Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome. Fluids Barriers CNS. 2022;19:74 pubmed 出版商
Kögel A, Fikenzer S, Uhlmann L, Opitz L, Kneuer J, Haeusler K, et al. Extracellular Inflammasome Particles Are Released After Marathon Running and Induce Proinflammatory Effects in Endothelial Cells. Front Physiol. 2022;13:866938 pubmed 出版商
Walter F, Harazin A, T xf3 th A, Veszelka S, Santa Maria A, Barna L, et al. Blood-brain barrier dysfunction in L-ornithine induced acute pancreatitis in rats and the direct effect of L-ornithine on cultured brain endothelial cells. Fluids Barriers CNS. 2022;19:16 pubmed 出版商
Yue Q, Zhou X, Zhang Z, Hoi M. Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors. Int J Mol Sci. 2022;23: pubmed 出版商
Khan M, Qiao F, Kumar P, Touhidul Islam S, Singh A, Won J, et al. Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms. Neural Regen Res. 2022;17:185-193 pubmed 出版商
Xu S, Bian H, Shu S, Xia S, Gu Y, Zhang M, et al. AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke. CNS Neurosci Ther. 2021;27:1224-1237 pubmed 出版商
Bhowmick S, Malat A, Caruso D, Ponery N, D Mello V, Finn C, et al. Intercellular Adhesion Molecule-1-Induced Posttraumatic Brain Injury Neuropathology in the Prefrontal Cortex and Hippocampus Leads to Sensorimotor Function Deficits and Psychological Stress. Eneuro. 2021;8: pubmed 出版商
Cao J, Wang B, Tang T, Wen Y, Li Z, Feng S, et al. Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury. Theranostics. 2021;11:5248-5266 pubmed 出版商
Offeddu G, Hajal C, Foley C, Wan Z, Ibrahim L, Coughlin M, et al. The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination. Commun Biol. 2021;4:255 pubmed 出版商
Beddek K, Raffin F, Borgel D, Saller F, Riccobono D, Bobe R, et al. TRPV4 channel activation induces the transition of venous and arterial endothelial cells toward a pro-inflammatory phenotype. Physiol Rep. 2021;9:e14613 pubmed 出版商
Charan M, Das S, Mishra S, Chatterjee N, Varikuti S, Kaul K, et al. Macrophage migration inhibitory factor inhibition as a novel therapeutic approach against triple-negative breast cancer. Cell Death Dis. 2020;11:774 pubmed 出版商
Reyes L, Getachew H, Dunn W, Progulske Fox A. Porphyromonas gingivalis W83 traffics via ICAM1 in microvascular endothelial cells and alters capillary organization in vivo. J Oral Microbiol. 2020;12:1742528 pubmed 出版商
Yokoyama S, Cai Y, Murata M, Tomita T, Yoneda M, Xu L, et al. A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death. elife. 2018;7: pubmed 出版商
Fu C, Yin D, Nie H, Sun D. Notoginsenoside R1 Protects HUVEC Against Oxidized Low Density Lipoprotein (Ox-LDL)-Induced Atherogenic Response via Down-Regulating miR-132. Cell Physiol Biochem. 2018;51:1739-1750 pubmed 出版商
Lo W, Yang W, Peng C, Pai W, Wang H. MicroRNA-200a/200b Modulate High Glucose-Induced Endothelial Inflammation by Targeting O-linked N-Acetylglucosamine Transferase Expression. Front Physiol. 2018;9:355 pubmed 出版商
Bulk E, Kramko N, Liashkovich I, Glaser F, Schillers H, Schnittler H, et al. KCa3.1 channel inhibition leads to an ICAM-1 dependent increase of cell-cell adhesion between A549 lung cancer and HMEC-1 endothelial cells. Oncotarget. 2017;8:112268-112282 pubmed 出版商
Okumura S, Uemura T, Zhao X, Masano Y, Tsuruyama T, Fujimoto Y, et al. Liver graft preservation using perfluorocarbon improves the outcomes of simulated donation after cardiac death liver transplantation in rats. Liver Transpl. 2017;23:1171-1185 pubmed 出版商
Liu J, Yang F, Yang X, Jankowski M, Pagano P. NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophy. Arterioscler Thromb Vasc Biol. 2003;23:776-82 pubmed
Kiarash A, Pagano P, Tayeh M, Rhaleb N, Carretero O. Upregulated Expression of Rat Heart Intercellular Adhesion Molecule-1 in Angiotensin II- but Not Phenylephrine- Induced Hypertension. Hypertension. 2001;37:58-65 pubmed
Yamazaki T, Seko Y, Tamatani T, Miyasaka M, Yagita H, Okumura K, et al. Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules. Am J Pathol. 1993;143:410-8 pubmed
Tamatani T, Kotani M, Miyasaka M. Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. Eur J Immunol. 1991;21:627-33 pubmed
图像
图像 1 :
赛默飞世尔 MA5407 图像 1
Immunohistochemistry was performed on normal biopsies of deparaffinized Mouse spleen tissue. To expose target proteins, heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1:100 with a mouse monoclonal antibody recognizing CD54 (MA5407) or without primary antibody (negative control) overnight at 4°C in a humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Detection was performed using a biotin-conjugated secondary antibody and SA-HRP, followed by colorimetric detection using DAB. Tissues were counterstained with hematoxylin and prepped for mounting.
图像 2 :
赛默飞世尔 MA5407 图像 2
Immunohistochemistry was performed on normal biopsies of deparaffinized Mouse kidney tissue. To expose target proteins, heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1:100 with a mouse monoclonal antibody recognizing CD54 (MA5407) or without primary antibody (negative control) overnight at 4°C in a humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Detection was performed using a biotin-conjugated secondary antibody and SA-HRP, followed by colorimetric detection using DAB. Tissues were counterstained with hematoxylin and prepped for mounting.
图像 3 :
赛默飞世尔 MA5407 图像 3
Immunohistochemistry was performed on normal biopsies of deparaffinized Mouse lung tissue. To expose target proteins, heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1:100 with a mouse monoclonal antibody recognizing CD54 (MA5407) or without primary antibody (negative control) overnight at 4°C in a humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Detection was performed using a biotin-conjugated secondary antibody and SA-HRP, followed by colorimetric detection using DAB. Tissues were counterstained with hematoxylin and prepped for mounting.
产品信息
产品类型 :
抗体
产品名称 :
ICAM-1单克隆抗体(1A29)
目录# :
MA5407
规格 :
500微克
价格 :
美国450.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunohistochemistry: 1:100, Neutralization: Assay-dependent, Western Blot: 1:250
物种 :
人类, 小鼠, 大鼠
克隆 :
1A29
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
免疫原 :
Rat lymph node stroma
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunohistochemistry: 1:100, Neutralization: Assay-dependent, Western Blot: 1:250
别名 :
BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国