产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD4 Monoclonal Antibody (RM4-5), PE-Texas Red
目录 :
MCD0417
规格 :
500微升
价格 :
美国290.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE Texas Red
克隆名称 :
RM4-5
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 13
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100; 图 3, 5
Aslan K, Turco V, Blobner J, Sonner J, Liuzzi A, Núñez N, et al. Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. Nat Commun. 2020;11:931 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Chuprin A, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A, et al. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nat Immunol. 2015;16:737-45 pubmed 出版商
  • 流式细胞仪; 小鼠
Saligrama N, Case L, Krementsov D, Teuscher C. Histamine H₂ receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis. FASEB J. 2014;28:1898-909 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Krementsov D, Wall E, Martin R, Subramanian M, Noubade R, del Rio R, et al. Histamine H(3) receptor integrates peripheral inflammatory signals in the neurogenic control of immune responses and autoimmune disease susceptibility. PLoS ONE. 2013;8:e62743 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 S1
Saligrama N, Case L, del Rio R, Noubade R, Teuscher C. Systemic lack of canonical histamine receptor signaling results in increased resistance to autoimmune encephalomyelitis. J Immunol. 2013;191:614-22 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Cravens P, Kieseier B, Hussain R, Herndon E, Arellano B, Ben L, et al. The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis. J Neuroinflammation. 2013;10:67 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Saligrama N, Noubade R, Case L, del Rio R, Teuscher C. Combinatorial roles for histamine H1-H2 and H3-H4 receptors in autoimmune inflammatory disease of the central nervous system. Eur J Immunol. 2012;42:1536-46 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Blankenhorn E, Butterfield R, Case L, Wall E, del Rio R, DIEHL S, et al. Genetics of experimental allergic encephalomyelitis supports the role of T helper cells in multiple sclerosis pathogenesis. Ann Neurol. 2011;70:887-96 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
del Rio R, Noubade R, Saligrama N, Wall E, Krementsov D, Poynter M, et al. Histamine H4 receptor optimizes T regulatory cell frequency and facilitates anti-inflammatory responses within the central nervous system. J Immunol. 2012;188:541-7 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Chen B, Cui X, Sempowski G, Domen J, Chao N. Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation. Blood. 2004;103:4344-52 pubmed
Casadesús A, Deligne C, Diallo B, Sosa K, Josseaume N, Mesa C, et al. A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy. Oncoimmunology. 2020;9:1770565 pubmed 出版商
Sagnella S, Yang L, Stubbs G, Boslem E, Martino Echarri E, Smolarczyk K, et al. Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells. Cancer Cell. 2020;37:354-370.e7 pubmed 出版商
Tse M, Lane C, Mott K, Onlamoon N, Hsiao H, Perng G. ICAM-5 modulates cytokine/chemokine production in the CNS during the course of herpes simplex virus type 1 infection. J Neuroimmunol. 2009;213:12-9 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD4 Monoclonal Antibody (RM4-5), PE-Texas Red
目录# :
MCD0417
规格 :
500微升
价格 :
美国290.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: Assay-dependent
物种 :
小鼠
克隆 :
RM4-5
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
免疫原 :
小鼠CD4
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent
别名 :
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国