产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
F4/80单克隆抗体(BM8), Alexa Fluor系列荧光染料488
目录 :
MF48020
规格 :
1毫升
价格 :
美国258
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
AF488
克隆名称 :
BM8
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 30
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 s2a
Al Zaeed N, Budai Z, Szondy Z, Sarang Z. TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice. Cell Death Dis. 2021;12:611 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6g
Petrovic I, Pejnovic N, Ljujic B, Pavlovic S, Miletic Kovacevic M, Jeftic I, et al. Overexpression of Galectin 3 in Pancreatic β Cells Amplifies β-Cell Apoptosis and Islet Inflammation in Type-2 Diabetes in Mice. Front Endocrinol (Lausanne). 2020;11:30 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, et al. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proc Natl Acad Sci U S A. 2018;115:E2801-E2810 pubmed 出版商
  • 流式细胞仪; 小鼠; 5:200; 图 6a
  • 免疫细胞化学; 小鼠; 5:200; 图 8a
Horsthemke M, Bachg A, Groll K, Moyzio S, Müther B, Hemkemeyer S, et al. Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion. J Biol Chem. 2017;292:7258-7273 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 5b
Schumacher M, Hedl M, Abraham C, Bernard J, Lozano P, Hsieh J, et al. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation. Cell Death Dis. 2017;8:e2622 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4a
Henkels K, Muppani N, Gomez Cambronero J. PLD-Specific Small-Molecule Inhibitors Decrease Tumor-Associated Macrophages and Neutrophils Infiltration in Breast Tumors and Lung and Liver Metastases. PLoS ONE. 2016;11:e0166553 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 st2
Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, et al. Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016;538:392-396 pubmed 出版商
  • 免疫组化; 小鼠; 图 3
Roy A, Femel J, Huijbers E, Spillmann D, Larsson E, Ringvall M, et al. Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma. PLoS ONE. 2016;11:e0156151 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 2
McCarthy R, Lu D, Alkhateeb A, Gardeck A, Lee C, Wessling Resnick M. Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta. J Neuroinflammation. 2016;13:21 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Hsiao H, Thatcher T, Colas R, Serhan C, Phipps R, Sime P. Resolvin D1 Reduces Emphysema and Chronic Inflammation. Am J Pathol. 2015;185:3189-201 pubmed 出版商
  • 流式细胞仪; 小鼠
Jovicic N, Jeftic I, Jovanovic I, Radosavljevic G, Arsenijevic N, Lukic M, et al. Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding. PLoS ONE. 2015;10:e0134089 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Shindo Y, Unsinger J, Burnham C, Green J, Hotchkiss R. Interleukin-7 and anti-programmed cell death 1 antibody have differing effects to reverse sepsis-induced immunosuppression. Shock. 2015;43:334-43 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 1
Rymo S, Gerhardt H, Wolfhagen Sand F, Lang R, Uv A, Betsholtz C. A two-way communication between microglial cells and angiogenic sprouts regulates angiogenesis in aortic ring cultures. PLoS ONE. 2011;6:e15846 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2
HogenEsch H, Dunham A, Seymour R, Renninger M, Sundberg J. Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice. Exp Dermatol. 2006;15:808-14 pubmed
  • 流式细胞仪; 小鼠
Mangan N, Van Rooijen N, McKenzie A, Fallon P. Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness. J Immunol. 2006;176:138-47 pubmed
  • 流式细胞仪; 小鼠; 图 3
Noel J, Guo X, Wells Byrum D, Schwemberger S, Caldwell C, Ogle C. Effect of thermal injury on splenic myelopoiesis. Shock. 2005;23:115-22 pubmed
  • 免疫组化-冰冻切片; 小鼠; 图 9
Malorny U, Michels E, Sorg C. A monoclonal antibody against an antigen present on mouse macrophages and absent from monocytes. Cell Tissue Res. 1986;243:421-8 pubmed
Walbaum S, Ambrosy B, Schütz P, Bachg A, Horsthemke M, Leusen J, et al. Complement receptor 3 mediates both sinking phagocytosis and phagocytic cup formation via distinct mechanisms. J Biol Chem. 2021;296:100256 pubmed 出版商
Kroeger C, Roesler R, Wiese S, Hainzl A, Gatzka M. Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors. Int J Mol Sci. 2020;21: pubmed 出版商
Ishimaru K, Yoshioka K, Kano K, Kurano M, Saigusa D, Aoki J, et al. Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation. Sci Rep. 2019;9:18329 pubmed 出版商
Sun D, Sun P, Li H, Zhang M, Liu G, Strickland A, et al. Fungal dissemination is limited by liver macrophage filtration of the blood. Nat Commun. 2019;10:4566 pubmed 出版商
Bachg A, Horsthemke M, Skryabin B, Klasen T, Nagelmann N, Faber C, et al. Phenotypic analysis of Myo10 knockout (Myo10tm2/tm2) mice lacking full-length (motorized) but not brain-specific headless myosin X. Sci Rep. 2019;9:597 pubmed 出版商
Zou A, Magee N, Deng F, Lehn S, Zhong C, Zhang Y. Hepatocyte nuclear receptor SHP suppresses inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis. J Biol Chem. 2018;293:8656-8671 pubmed 出版商
Peuhu E, Salomaa S, De Franceschi N, Potter C, Sundberg J, Pouwels J. Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice. PLoS ONE. 2017;12:e0186628 pubmed 出版商
Chakraborty K, Raundhal M, Chen B, Morse C, Tyurina Y, Khare A, et al. The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia. Nat Commun. 2017;8:13944 pubmed 出版商
Mani R, Amin M, Li X, Kalyana Sundaram S, Veeneman B, Wang L, et al. Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer. Cell Rep. 2016;17:2620-2631 pubmed 出版商
Cipriani G, Gibbons S, Verhulst P, Choi K, Eisenman S, Hein S, et al. Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying. Cell Mol Gastroenterol Hepatol. 2016;2:40-47 pubmed
Trikha P, Sharma N, Pena C, Reyes A, Pécot T, Khurshid S, et al. E2f3 in tumor macrophages promotes lung metastasis. Oncogene. 2016;35:3636-46 pubmed 出版商
Smith K, Hochweller K, Hämmerling G, Boon L, MacDonald A, Maizels R. Chronic helminth infection promotes immune regulation in vivo through dominance of CD11cloCD103- dendritic cells. J Immunol. 2011;186:7098-109 pubmed 出版商
Jun D, Garat C, West J, Thorn N, Chow K, Cleaver T, et al. The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation. Stem Cells. 2011;29:725-35 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
F4/80单克隆抗体(BM8), Alexa Fluor系列荧光染料488
目录# :
MF48020
规格 :
1毫升
价格 :
美国258
克隆性 :
单克隆
纯度 :
纯化
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: Assay-dependent
物种 :
小鼠
克隆 :
BM8
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.
免疫原 :
mouse F4/80 which is a macrophage-restricted cell surface glycoprotein.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent
别名 :
ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国